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CD160 Antibody (12-1609-42) in Flow
Staining of normal human peripheral blood cells with Anti-Human CD56 (NCAM) PerCP-eFluor® 710 (Product # 46-0567-42) and Mouse IgG2b K Isotype Control PE (Product # 12-4732-81) (left) or Anti-Human CD160 PE (right). Cells in the lymphocyte gate were used for analysis.
产品信息
12-1609-42
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
BY55
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
5 µL/Test
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 0.2% BSA
内含物
0.09% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2572583
产品详细信息
Description: This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on natural killer cells, natural killer T cells, activated and/or memory CD4 and CD8 T cells, gamma delta T cells, and intraepithelial cells. CD160 has been reported to bind herpes virus entry mediator (HVEM) in a complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells that abrogates proliferation and cytokine production. Three alternative splice variants of CD160 have also been identified in natural killer cells.
Applications Reported: This BY55 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This BY55 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
Filtration: 0.2 µm post-manufacturing filtered.
靶标信息
CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. It is involved in cell proliferation, cell surface receptor signaling pathways, cellular defense response, and regulation of immune response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
生物信息学
蛋白别名: CD160; CD160 antigen; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell receptor; Natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member
基因别名: BY55; CD160; NK1; NK28
UniProt ID: (Human) B8PRF2
Entrez Gene ID: (Human) 11126
