Invitrogen

CD200 Monoclonal Antibody (325516), APC

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CD200 Antibody (MA5-23575) in Flow

Flow cytometry of CD200 in Th17 differentiated human peripheral blood mononuclear cells (PBMCs). Samples were incubated in CD200 monoclonal antibody (Product # MA5-23575) followed by Mouse Anti-Human CD3ε PE-conjugated Monoclonal Antibody. Quadrant markers were set based on control antibody staining.

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产品信息

MA5-23575

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

10 µL per million cells

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

325516

抗原

Mouse myeloma cell line NS0-derived recombinant human CD200 Gln31-Gly232

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偶联物

APC APC APC

激发/发射光谱

651/660 nm 查看光谱

形式

Liquid

纯化类型

Protein A/G

保存液

Buffered saline solution with BSA

内含物

0.09% sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2608819

产品详细信息

In direct ELISAs, no cross-reactivity with recombinant mouse CD200 is observed.

靶标信息

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.

仅用于科研。不用于诊断过程。未经明确授权不得转售。