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产品信息
17842-1-AP
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CD226 Fusion Protein Ag12206 (1-254 aa encoded by BC074787)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDYPTLLLA LLHVYRALCE EVLWHTSVPF AENMSLECVY PSMGILTQVE WFKIGTQQDS IAIFSPTHGM VIRKPYAERV YFLNSTMASN NMTLFFRNAS EDDVGYYSCS LYTYPQGTWQ KVIQVVQSDS FEAAVPSNSH IVSEPGKNVT LTCQPQMTWP VQAVRWEKIQ PRQIDLLTYC NLVHGRNFTS KFPRQIVSNC SHGRWSVIVI PDVTVSDSGL YRCYLQASAG ENETFVMRLT VAEGKTDNQY TLFVA (1-254 aa encoded by BC074787)
靶标信息
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: adhesion glycoprotein; CD226; CD226 antigen; DNAM 1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen
基因别名: CD226; DNAM-1; DNAM1; PTA1; TLiSA1
UniProt ID: (Human) Q15762
Entrez Gene ID: (Human) 10666
cytokine production
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
positive regulation of immunoglobulin mediated immune response
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
cell recognition
positive regulation of mast cell activation
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
positive regulation of Fc receptor mediated stimulatory signaling pathway
