Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
CD226 (DNAM-1) Antibody (MA5-28148) in Flow
Flow cytometry of CD226 (DNAM-1) in red cell lysed human blood. Sample was incubated in the presence of 10% dog serum, CD226 (DNAM-1) monoclonal antibody (Product # MA5-28148) and gated on lymphoid cells. Figures are arranged as follows: A) Alexa Fluor 488 conjugated Mouse anti Human CD3 and PE-Alexa Fluor 647 conjugated Mouse IgG1 isotype control. B) Alexa Fluor 488 conjugated Mouse anti Human CD3 and PE-Alexa Fluor 647 conjugated Mouse anti Human CD226.
产品信息
MA5-28148
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
DX11
抗原
Human cytotoxic T lymphocyte clone
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein A
保存液
PBS with 1% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745128
产品详细信息
This antibody recognizes human CD226, approximately a 65 kDa glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells.
靶标信息
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
生物信息学
蛋白别名: adhesion glycoprotein; CD226; CD226 antigen; DNAM 1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen
基因别名: CD226; DNAM-1; DNAM1; PTA1; TLiSA1
UniProt ID: (Human) Q15762
Entrez Gene ID: (Human) 10666
cytokine production
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
positive regulation of immunoglobulin mediated immune response
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
cell recognition
positive regulation of mast cell activation
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
positive regulation of Fc receptor mediated stimulatory signaling pathway
