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产品信息
CD3-301AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 131-181 on human T-cell surface glycoprotein CD3 gamma protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
靶标信息
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain
基因别名: CD3-GAMMA; CD3G; Ctg-3; Ctg3; IMD17; T3G
UniProt ID: (Human) P09693, (Mouse) P11942
Entrez Gene ID: (Human) 917, (Mouse) 12502
establishment or maintenance of cell polarity
cell surface receptor signaling pathway
protein transport
regulation of lymphocyte apoptotic process
protein complex assembly
T cell costimulation
Fc-gamma receptor signaling pathway involved in phagocytosis
T cell activation
regulation of immune response
T cell receptor signaling pathway
