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产品信息
MA1-10190
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
MEM-260
抗原
HPB human acute lymphoid leukemia cell line
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152437
产品详细信息
This antibody reacts with an extracellular epitope of CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T cells and 15% of circulating B cells.
Western Blot: non-reducing conditions.
靶标信息
The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998 [PubMed 9701027]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen-like family member A; CD300a; CD300a antigen; CLM-8; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35HIRp60; IgSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1/IRC2; IRp60; leukocyte membrane antigen; Mcipr1; NK inhibitory receptor; NKRL
基因别名: CD300A; CLM-8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35H; CMRF35H9; HSPC083; IGSF12; IRC1; IRC1/IRC2; IRC2; IRp60
UniProt ID: (Human) Q9UGN4
Entrez Gene ID: (Human) 11314
immune system process
cell adhesion
signal transduction
negative regulation of B cell proliferation
positive regulation of phosphoprotein phosphatase activity
negative regulation of mast cell activation involved in immune response
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
negative regulation of fibroblast proliferation
regulation of immune response
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of activation of JAK2 kinase activity
negative regulation of eosinophil migration
