Loading ...

Invitrogen

CD31 Polyclonal Antibody

9 篇参考文献

查看其他177个CD31 (PECAM-1)抗体

说明书

实验方案

技术支持

货号 PA5-24411

CNY 5,820.00

400 µL

查看价格

批量或定制请求

说明书

实验方案

技术支持

抗体检测数据 (2)

Application

图: 1 / 2

CD31 Antibody (PA5-24411) in WB

Western blot analysis of CD31 in mouse liver lysate. Samples were incubated with CD31 polyclonal antibody (Product # PA5-24411) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 81 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

Product Image Gallery

产品信息

PA5-24411

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000

查看1篇已发表文章 1篇已发表文章

免疫组化 (IHC)

查看6篇已发表文章 6篇已发表文章

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

流式细胞分析 (Flow)

1:25

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Hamster, Mouse

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of mouse CD31

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2541911

靶标信息

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Exerkine apelin reverses obesity-associated placental dysfunction by accelerating mitochondrial biogenesis in mice.

American journal of physiology. Endocrinology and metabolism

Chae SA,Son JS,Zhao L,Gao Y,Liu X,Marie de Avila J,Zhu MJ,Du M

PA5-24411 was used in Western Blotting to investigate the role of maternal exercise (ME) in protecting against adverse effects of maternal obesity (MO) on fetal development.

Wed Jun 01 00:00:00 UTC 2022

Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.

Cell reports

Son JS,Chae SA,Wang H,Chen Y,Bravo Iniguez A,de Avila JM,Jiang Z,Zhu MJ,Du M

PA5-24411 was used in Immunohistochemistry to investigate the effects of maternal exercise on offspring muscle metabolic health.

Tue Dec 01 00:00:00 UTC 2020

Endothelial LSP1 Modulates Extravascular Neutrophil Chemotaxis by Regulating Nonhematopoietic Vascular PECAM-1 Expression.

Journal of immunology (Baltimore, Md. : 1950)

Hossain M,Qadri SM,Xu N,Su Y,Cayabyab FS,Heit B,Liu L

PA5-24411 was used in immunohistochemistry to study cell-specific function of LSP1 during leukocyte recruitment

Tue Sep 01 00:00:00 UTC 2015

The effect of metanephros transplantation on blood pressure in anephric rats with induced acute hypotension.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Yokote S,Yokoo T,Matsumoto K,Utsunomiya Y,Kawamura T,Hosoya T

PA5-24411 was used in immunohistochemistry to study the role of metanephros transplantation in maintaining blood pressure in hypotensive anephric rats

Sat Sep 01 00:00:00 UTC 2012

Adipose tissue explants and MDCK cells reciprocally regulate their morphogenesis in coculture.

Kidney international

Udo K,Aoki S,Uchihashi K,Kawasaki M,Matsunobu A,Tokuda Y,Ootani A,Toda S,Uozumi J

PA5-24411 was used in immunohistochemistry to study the reciprocal regulation of morphogenesis in co-cultures of adipose tissue explants and MDCK cells

Thu Jul 01 00:00:00 UTC 2010

Combination of vesicular stomatitis virus matrix protein gene therapy with low-dose cisplatin improves therapeutic efficacy against murine melonoma.

Cancer science

Luo S,Chen P,Luo ZC,Zhang P,Sun P,Shi W,Li ZY,Zhang XL,Wang LQ,Chen X,Wei YQ,Wen YJ

PA5-24411 was used in immunohistochemistry to study the therepeutic efficacy of vesicular stomatitis virus matrix protein gene therapy plus low-dose cisplatin against murine melonoma

Sat May 01 00:00:00 UTC 2010

CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes.

Journal of immunology (Baltimore, Md. : 1950)

Tzeng TC,Chyou S,Tian S,Webster B,Carpenter AC,Guaiquil VH,Lu TT

PA5-24411 was used in immunohistochemistry to study the role of CD11c(hi)-expressing dendritic cells in the regulation of quiescence and stabilization of new vasculature following immune stimulation of lymph nodes

Thu Apr 15 00:00:00 UTC 2010

A new organotypic culture of adipose tissue fragments maintains viable mature adipocytes for a long term, together with development of immature adipocytes and mesenchymal stem cell-like cells.

Endocrinology

Sonoda E,Aoki S,Uchihashi K,Soejima H,Kanaji S,Izuhara K,Satoh S,Fujitani N,Sugihara H,Toda S

PA5-24411 was used in immunocytochemistry and immunohistochemistry to develop a new culture system for studying multiple cell types within adipose tissue

Wed Oct 01 00:00:00 UTC 2008

Antimetastatic effect of suicide gene therapy for mouse mammary cancers requires T-cell-mediated immune responses.

Medical molecular morphology

Shibata MA,Morimoto J,Akamatsu K,Otsuki Y

PA5-24411 was used in immunohistochemistry to study the role of T-cell-mediated immune responses in the antimetastatic effect of suicide gene therapy of mouse mammary cancers

Sat Mar 01 00:00:00 UTC 2008

生物信息学

蛋白别名: CD31; PECAM-1; Platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1

基因别名: C85791; Cd31; I79_008304; Pecam; PECAM-1; Pecam1

UniProt ID: (Mouse) Q08481

Entrez Gene ID: (Chinese hamster) 100774872, (Mouse) 18613

功能

immunoglobulin receptor superfamily

CD31 Polyclonal Antibody

CD31 Antibody (PA5-24411) in WB

产品信息

PA5-24411

免疫印迹 (WB)

免疫组化 (IHC)

免疫细胞化学 (ICC/IF)

流式细胞分析 (Flow)

其他PubMed (Misc)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

CD31 Polyclonal Antibody

CD31 Antibody (PA5-24411) in WB

产品信息

PA5-24411

免疫印迹 (WB)

免疫组化 (IHC)

免疫细胞化学 (ICC/IF)

流式细胞分析 (Flow)

其他PubMed (Misc)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#A2A2A2;}

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

RRID