Invitrogen

CD31 Monoclonal Antibody (TLD-3A12), FITC

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CD31 Antibody (MA5-16952) in Flow

Molecular medicine reports 2020 - Figure 1. Isolation and identification of rat pMSCs. (A) Primary culture and P2 generation cell morphology (magnification, x100). (B) The three on the left panels are unstained negative controls of flow cytometry analysis, while the six on the right are the quantitative analysis of CD44, CD90, CD29, CD31, CD45 and CD11b/c. (C) Immunofluorescence staining of pMSCs. (a and b) Control group. (c and d) Experime... View More

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产品信息

MA5-16952

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Neat

查看3篇已发表文章 3篇已发表文章

产品规格

种属反应

Rhesus monkey, Rat

已发表种属

Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

TLD-3A12

抗原

Activated, Lewis rat derived microglial cells

查看免疫原

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Protein A

保存液

PBS with 1% BSA

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2538427

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

靶标信息

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

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Science advances

Li L,Yao ZC,Parian A,Yang YH,Chao J,Yin J,Salimian KJ,Reddy SK,Zaheer A,Gearhart SL,Mao HQ,Selaru FM

MA5-16952 was used in flow cytometry to demonstrate that ADSC-loaded mfNHC is a promising therapy for CD-PAF, and warrants further studies to advance mfNHC toward clinical translation.

Wed Jan 04 00:00:00 EST 2023

Anti-streptococcal antibody and T-cell interactions with vascular endothelial cells initiate the development of rheumatic carditis.

Journal of leukocyte biology

Sikder S,Rush CM,Govan BL,Alim MA,Ketheesan N

Published figure using CD31 monoclonal antibody (Product # MA5-16952) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats.

Molecular medicine reports

Yuan W,Song HY,Xiong J,Jiang WL,Kang GJ,Huang J,Xie SP

MA5-16952 was used in Flow cytometry/Cell sorting to demonstrate placenta‚derived mesenchymal stem cells could be used as therapy for lipopolysaccharide (LPS)‚induced acute lung injury.

Sat Aug 01 00:00:00 EDT 2020

Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats.

Molecular medicine reports

Yuan W,Song HY,Xiong J,Jiang WL,Kang GJ,Huang J,Xie SP

MA5-16952 was used in Flow cytometry/Cell sorting to demonstrate placenta‚derived mesenchymal stem cells could be used as therapy for lipopolysaccharide (LPS)‚induced acute lung injury.