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CD37 Antibody (MA5-48039) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of CD37 in Daudi cells using CD37 Recombinant Monoclonal Antibody (Product # MA5-48039). Paraformaldehyde-fixed cells were stained with CD37 Recombinant Monoclonal Antibody at 10 µg/mL followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom CD37 Recombinant Monoclonal Antibody, DAPI, merged channels and an isotype control. The isotype control was stained with Mouse IgG1 Isotype Control Antib... View More
产品信息
MA5-48039
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
MB-1
抗原
BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3074482
产品详细信息
Specificity: This antibody is specific for human CD37, which is expressed on virtually all mature B lymphocytes, but not on pro-B or plasma cells. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 does not appear to be expressed on T cells, thymocytes, granulocytes or platelets.
Preparation: BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma. Immunophenotyping studies of these cells identified them as B cells expressing SIgG/lambda, as well as HLA-DR. Leu-12, and B1.
靶标信息
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD37; cell differentiation antigen 37; Leukocyte antigen CD37; leukocyte surface antigen CD37; Tetraspanin-26; Tspan-26
基因别名: CD37; GP52-40; TSPAN26
UniProt ID: (Human) P11049
Entrez Gene ID: (Human) 951
