Invitrogen

CD38 Monoclonal Antibody (HIT2), FITC

产品信息

MHCD3801

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-Dependent

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其他PubMed (Misc)

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

抗原

Human CD38

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

纯化类型

purified

保存液

PBS with 4mg/mL BSA

内含物

0.1% sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_10373808

产品详细信息

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

靶标信息

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.

Analyte Specific Reagent

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients.

Immunology

de Oliveira AL,Amadeu TP,de França Gomes AC,Menezes VM,da Costa Nery JA,Pinheiro RO,Sarno EN

MHCD3801 was used in Flow cytometry/Cell sorting to study the role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients.

Sun Sep 01 00:00:00 EDT 2013

Identification of four human cDNAs that are differentially expressed by early hematopoietic progenitors.

Experimental hematology

Zhang X,Dormady SP,Basch RS

MHCD3801 was used in flow cytometry to elucidate the molecular processes that maintain the stem cell pool.

Wed Nov 01 00:00:00 EST 2000

Different behaviour of fresh and cultured CD34+ cells during immunomagnetic separation.

British journal of haematology

Denning-Kendall PA,Horsley H,Donaldson C,Bradley B,Hows JM

MHCD3801 was used in flow cytometry to characterize CD34+ cells derived from human cord blood after culture.

Tue Jun 01 00:00:00 EDT 1999

Expression, regulation, and function of B cell-expressed CD154 in germinal centers.

Journal of immunology (Baltimore, Md. : 1950)

Grammer AC,McFarland RD,Heaney J,Darnell BF,Lipsky PE

MHCD3801 was used in flow cytometry to investigate the expression and function of B cell CD154.

Fri Oct 15 00:00:00 EDT 1999

Characterization of endogenous protoporphyrin IX induced by delta-aminolevulinic acid in resting and activated peripheral blood lymphocytes by four-color flow cytometry.

Photochemistry and photobiology

Hryhorenko EA,Rittenhouse-Diakun K,Harvey NS,Morgan J,Stewart CC,Oseroff AR

MHCD3801 was used in flow cytometry to determine the effects of delta-aminolevulinic acid and delta-aminolevulinic acid-photodynamic therapy on resting and activated human peripheral blood T lymphocytes.

Fri May 01 00:00:00 EDT 1998

Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathway.

The Journal of experimental medicine

van der Voort R,Taher TE,Keehnen RM,Smit L,Groenink M,Pals ST

MHCD3801 was used in flow cytometry to identify c-met-encoded receptor tyrosine kinase and its ligand, HGF/SF, as a novel paracrine signaling pathway that regulates B cell adhesion.

Mon Jun 16 00:00:00 EDT 1997

FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver.

Blood

Muench MO,Roncarolo MG,Menon S,Xu Y,Kastelein R,Zurawski S,Hannum CH,Culpepper J,Lee F,Namikawa R

MHCD3801 was used in flow cytometry to assess the effects of the FLK-2/FLT-3 ligand on the growth of human fetal liver progenitors.

Wed Feb 15 00:00:00 EST 1995

生物信息学

蛋白别名: 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADPRC 1; cADPR hydrolase 1; CD38; CD38 antigen (p45); CD38 antigen p45; cluster of differentiation 38; Cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; NAD(+) nucleosidase; NAD+ nucleosidase; T10

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基因别名: ADPRC 1; ADPRC1; CD38

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UniProt ID: (Human) P28907

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Entrez Gene ID: (Human) 952

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功能

NAD+ nucleosidase activity transferase activity phosphorus-oxygen lyase activity NAD(P)+ nucleosidase activity cyclase lyase metabolite interconversion enzyme

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