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产品信息
MA5-28684
产品规格
种属反应
Avian,
Chicken
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
CT-4
抗原
Chicken thymocytes and Ig-negative blood leukocytes
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
purified
保存液
PBS, pH 7.4
内含物
<0.1% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745643
靶标信息
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
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生物信息学
蛋白别名: CD4; CD4 antigen (p55); CD4 antigen p55; cd4a; fCD4; Leu-3; membrane protein
Entrez Gene ID: (Chicken) 395362
