Invitrogen

CD4 Monoclonal Antibody (RPA-T4), Biotin, eBioscience™

高级验证

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

57个已发表图片

49 篇参考文献

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说明书

实验方案

技术支持

说明书

实验方案

技术支持

图: 1 / 59

CD4 Antibody (13-0049-82) in Flow

Normal human peripheral blood stained with Anti-Human CD4 Biotin and detected with Streptavidin PE (Product # 12-4317-87). Cells in the lymphocyte gate were analyzed.

CD4 Antibody in Immunocytochemistry (ICC/IF)

CD4 Antibody in Immunohistochemistry (IHC)

CD4 Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)

Product Image Gallery

CD4 Antibody — Figure 7 LIF-nano induce expansion of FOXP3+ CD4+ CD25+ T lymphocytes of the rhesus monkey Peripheral blood lymphocytes (pbl) from 2 alloreactive rhesus monkeys were set up in a one way MLR (see methods). After 7d the cultures were boosted with irradiated donor pbl. Nine culture conditions were applied, as indicated. Both the LIF-nano and the empty-nano were targeted to CD4. The culture sets of 9 conditions were replicated for assaying by flow cytometry at 7d, prior to boosting (left-hand panels), and at 11d, 4d after boost (right-hand panels). (A) Analysis of the CD4+ cell population for FOXP3 (axis) and CD25 (abcissa) expression at 7d, and at 11d. (B) Total numbers of CD4+ cells in each culture at 11d shown as (i) all CD4+ cells (white fill); (ii) all dual CD4+ FOXP3+ cells (striped fill); and (iii) all triple positive CD4+ FOXP3+ CD25+ cells (black fill). Percentages are relative to controls. {TM}

产品信息

13-0049-82

应用

建议稀释比

已发表文章

免疫组化 (IHC)

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免疫细胞化学 (ICC/IF)

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流式细胞分析 (Flow)

1 µg/test

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酶联免疫吸附实验 (ELISA)

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中和实验 (Neu)

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功能检测 (Functional)

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产品规格

种属反应

Human

已发表种属

Hamster, Human, Rhesus monkey

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

RPA-T4

偶联物

Biotin Biotin Biotin

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.09% sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_466337

产品详细信息

Description: The RPA-T4 monoclonal antibody reacts with human CD4, a 59 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells (T-helper cells) and in low levels on monocytes. CD4 is a receptor for the human immunodeficiency virus (HIV). RPA-T4 blocks HIV binding and mixed lymphocyte reaction. The RPA-T4 antibody recognizes a different epitope than the OKT4 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes.

Applications Reported: The RPA-T4 antibody has been reported for use in flow cytometric analysis.

Applications Tested: The RPA-T4 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Filtration: 0.2 µm post-manufacturing filtered.

靶标信息

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.

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Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

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Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes.

JCI insight

Zhang M,Chong KK,Chen ZY,Guo H,Liu YF,Kang YY,Li YJ,Shi TT,Lai KK,He MQ,Ye K,Kahaly GJ,Shi BY,Wang Y

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Wed Feb 08 00:00:00 EST 2023

Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor.

Cells

Rode AKO,Buus TB,Mraz V,Al-Jaberi FAH,Lopez DV,Ford SL,Hennen S,Eliasen IP,Klewe IV,Gharehdaghi L,Dragan A,Rosenkilde MM,Woetmann A,Skov L,Ødum N,Bonefeld CM,Kongsbak-Wismann M,Geisler C

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Immunohistochemistry

Fri Aug 19 00:00:00 EDT 2022

Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.

Frontiers in immunology

Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Mon Jan 30 00:00:00 EST 2023

Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.

Nature communications

McEvoy CM,Murphy JM,Zhang L,Clotet-Freixas S,Mathews JA,An J,Karimzadeh M,Pouyabahar D,Su S,Zaslaver O,Röst H,Arambewela R,Liu LY,Zhang S,Lawson KA,Finelli A,Wang B,MacParland SA,Bader GD,Konvalinka A,Crome SQ

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Sat Dec 10 00:00:00 EST 2022

Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.

Cell discovery

Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue May 10 00:00:00 EDT 2022

Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells.

Biomolecules & therapeutics

Yoon H,Sung JH,Song MJ

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.

Cancers

Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue Apr 13 00:00:00 EDT 2021

Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.

Molecular therapy. Methods & clinical development

Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Fri Sep 10 00:00:00 EDT 2021

Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.

Frontiers in immunology

Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Oct 21 00:00:00 EDT 2021

Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.

Cancer immunology, immunotherapy : CII

Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2020

HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.

Journal of Cancer

Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.

The Journal of international medical research

He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2020

Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells.

Frontiers in immunology

Møller SH,Mellergaard M,Madsen M,Bermejo AV,Jepsen SD,Hansen MH,Høgh RI,Aldana BI,Desler C,Rasmussen LJ,Sustarsic EG,Gerhart-Hines Z,Daskalaki E,Wheelock CE,Hiron TK,Lin D,O'Callaghan CA,Wandall HH,Andresen L,Skov S

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Neutralization

Fri Apr 30 00:00:00 EDT 2021

Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.

Journal of biological methods

Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.

Molecular medicine reports

Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming.

eLife

Francesconi M,Di Stefano B,Berenguer C,de Andrés-Aguayo L,Plana-Carmona M,Mendez-Lago M,Guillaumet-Adkins A,Rodriguez-Esteban G,Gut M,Gut IG,Heyn H,Lehner B,Graf T

13-0049 was used in Flow cytometry/Cell sorting to elucidate how single cell expression and computational analyses can identify the origins of heterogeneity in cell fate conversion processes.

Tue Mar 12 00:00:00 EDT 2019

RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.

Cell

Bradley T,Peppa D,Pedroza-Pacheco I,Li D,Cain DW,Henao R,Venkat V,Hora B,Chen Y,Vandergrift NA,Overman RG,Edwards RW,Woods CW,Tomaras GD,Ferrari G,Ginsburg GS,Connors M,Cohen MS,Moody MA,Borrow P,Haynes BF

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Oct 04 00:00:00 EDT 2018

The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.

Acta Cardiologica Sinica

Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Sat Sep 01 00:00:00 EDT 2018

Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.

Cell

Horwitz JA,Bar-On Y,Lu CL,Fera D,Lockhart AAK,Lorenzi JCC,Nogueira L,Golijanin J,Scheid JF,Seaman MS,Gazumyan A,Zolla-Pazner S,Nussenzweig MC

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Aug 10 00:00:00 EDT 2017

Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease.

Cell

Van Dyken SJ,Liang HE,Naikawadi RP,Woodruff PG,Wolters PJ,Erle DJ,Locksley RM

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Apr 20 00:00:00 EDT 2017

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

Cell

Lim AI,Li Y,Lopez-Lastra S,Stadhouders R,Paul F,Casrouge A,Serafini N,Puel A,Bustamante J,Surace L,Masse-Ranson G,David E,Strick-Marchand H,Le Bourhis L,Cocchi R,Topazio D,Graziano P,Muscarella LA,Rogge L,Norel X,Sallenave JM,Allez M,Graf T,Hendriks RW,Casanova JL,Amit I,Yssel H,Di Santo JP

13-0049 was used in Flow cytometry/Cell sorting to identify circulating and tissue ILC precursors in humans that fail to express the transcription factors and cytokine outputs of mature ILCs but have these signature loci in an epigenetically poised configuration.

Thu Mar 09 00:00:00 EST 2017

Blocking the recruitment of naive CD4⁺ T cells reverses immunosuppression in breast cancer.

Cell research

Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Sat Apr 01 00:00:00 EDT 2017

Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.

Frontiers in immunology

Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.

Journal of leukocyte biology

de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritis.

RMD open

Yamada H,Haraguchi A,Sakuraba K,Okazaki K,Fukushi JI,Mizu-Uchi H,Akasaki Y,Esaki Y,Kamura S,Fujimura K,Kondo M,Miyahara H,Nakashima Y,Yoshikai Y

13-0049 was used in Flow cytometry/Cell sorting to suggest the presence of common developmental pathway for these T cells.

Wed Nov 20 00:00:00 EST 2019

CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.

JCI insight

Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Fri Jun 02 00:00:00 EDT 2017

CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.

JCI insight

Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Fri Jun 02 00:00:00 EDT 2017

Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.

Proceedings of the National Academy of Sciences of the United States of America

Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Immunofluorescence

Tue May 17 00:00:00 EDT 2016

Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.

Proceedings of the National Academy of Sciences of the United States of America

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Immunofluorescence

Tue May 17 00:00:00 EDT 2016

Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.

Arthritis research & therapy

Noack M,Ndongo-Thiam N,Miossec P

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Jun 23 00:00:00 EDT 2016

CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.

Molecular medicine reports

Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.

Experimental and therapeutic medicine

Zhao J,Ma J,Zhang X,Li Q,Yang X

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2016

Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.

Scientific reports

Kumar A,Abbas W,Colin L,Khan KA,Bouchat S,Varin A,Larbi A,Gatot JS,Kabeya K,Vanhulle C,Delacourt N,Pasquereau S,Coquard L,Borch A,König R,Clumeck N,De Wit S,Rohr O,Rouzioux C,Fulop T,Van Lint C,Herbein G

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Apr 14 00:00:00 EDT 2016

Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.

Stem cell reports

Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue Oct 11 00:00:00 EDT 2016

Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Sun Nov 01 00:00:00 EDT 2015

Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.

Oncoimmunology

Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Thu Jan 01 00:00:00 EST 2015

dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.

Nature communications

Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue Sep 15 00:00:00 EDT 2015

Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.

PloS one

Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Wed Dec 30 00:00:00 EST 2015

Immune response to JC virus T antigen in patients with and without colorectal neoplasia.

Gut microbes

Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue Jul 01 00:00:00 EDT 2014

OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Graves AJ,Padilla MG,Hokey DA

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Tue Jul 01 00:00:00 EDT 2014

Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.

Cancer immunology research

Choi BD,Gedeon PC,Herndon JE,Archer GE,Reap EA,Sanchez-Perez L,Mitchell DA,Bigner DD,Sampson JH

Published figure using CD4 monoclonal antibody (Product # 13-0049-82) in Flow Cytometry

Sun Sep 01 00:00:00 EDT 2013

Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases.

PloS one

Tseng WY,Huang YS,Chiang NY,Chou YP,Wu YJ,Luo SF,Kuo CF,Lin KM,Lin HH

13-0049 was used in an ELISA assay to explore how, and why, higher levels of soluble CD4 are produced in patients of infectious and chronic inflammatory diseases.

Mon Nov 25 00:00:00 EST 2013

Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases.

PloS one

Tseng WY,Huang YS,Chiang NY,Chou YP,Wu YJ,Luo SF,Kuo CF,Lin KM,Lin HH

13-0049 was used in an ELISA assay to explore how, and why, higher levels of soluble CD4 are produced in patients of infectious and chronic inflammatory diseases.