Product References
Human osteoarthritic articular cartilage stem cells suppress osteoclasts and improve subchondral bone remodeling in experimental knee osteoarthritis partially by releasing TNFAIP3.
Stem cell research & therapy
Li ZL,Li XT,Hao RC,Wang FY,Wang YX,Zhao ZD,Li PL,Yin BF,Mao N,Ding L,Zhu H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Sep 27 00:00:00 EDT 2023
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Platelet factors attenuate inflammation and rescue cognition in ageing.
Nature
Schroer AB,Ventura PB,Sucharov J,Misra R,Chui MKK,Bieri G,Horowitz AM,Smith LK,Encabo K,Tenggara I,Couthouis J,Gross JD,Chan JM,Luke A,Villeda SA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine.
Cell reports. Medicine
Dan J,Cai J,Zhong Y,Wang C,Huang S,Zeng Y,Fan Z,Xu C,Hu L,Zhang J,Hu J,Liu Y,Su X,Zhu W,Yan G,Liang J,Lin Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2023
Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self.
Cell reports
Geiger KM,Manoharan M,Coombs R,Arana K,Park CS,Lee AY,Shastri N,Robey EA,Coscoy L
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Apr 25 00:00:00 EDT 2023
Exercise combined with administration of adipose-derived stem cells ameliorates neuropathic pain after spinal cord injury.
Neural regeneration research
Cheng X,Mao GP,Hu WJ,Yu ZR,Xu YY,Chen W,Li X,Zeng XL,Zhang WW,Chen JW,Wan Y,Wang L
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions.
Frontiers in immunology
O'Neill TJ,Gewies A,Seeholzer T,Krappmann D
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2023
Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response.
Nature communications
Arora R,Cao C,Kumar M,Sinha S,Chanda A,McNeil R,Samuel D,Arora RK,Matthews TW,Chandarana S,Hart R,Dort JC,Biernaskie J,Neri P,Hyrcza MD,Bose P
14-0441-82 was used in Immunocytochemistry to characterize malignant cells in tumor core (TC) and leading edge (LE) transcriptional architectures.
Fri Aug 18 00:00:00 EDT 2023
Mitochondrial RNA modifications shape metabolic plasticity in metastasis.
Nature
Delaunay S,Pascual G,Feng B,Klann K,Behm M,Hotz-Wagenblatt A,Richter K,Zaoui K,Herpel E,Münch C,Dietmann S,Hess J,Benitah SA,Frye M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2022
Mitochondrial RNA modifications shape metabolic plasticity in metastasis.
Nature
Delaunay S,Pascual G,Feng B,Klann K,Behm M,Hotz-Wagenblatt A,Richter K,Zaoui K,Herpel E,Münch C,Dietmann S,Hess J,Benitah SA,Frye M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2022
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury.
The Journal of clinical investigation
Sato Y,Oguchi A,Fukushima Y,Masuda K,Toriu N,Taniguchi K,Yoshikawa T,Cui X,Kondo M,Hosoi T,Komidori S,Shimizu Y,Fujita H,Jiang L,Kong Y,Yamanashi T,Seita J,Yamamoto T,Toyokuni S,Hamazaki Y,Hattori M,Yoshikai Y,Boor P,Floege J,Kawamoto H,Murakawa Y,Minato N,Yanagita M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Jan 18 00:00:00 EST 2022
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
Frontiers in oncology
Dolatabadi S,Jonasson E,Andersson L,Luna Santamaría M,Lindén M,Österlund T,Åman P,Ståhlberg A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Feb 23 00:00:00 EST 2022
LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells.
Scientific reports
Xu Y,Cao L,Ji S,Shen W
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Oct 27 00:00:00 EDT 2022
Isolation and characterization mesenchymal stem cells from red panda (Ailurus fulgens styani) endometrium.
Conservation physiology
Wang DH,Wu XM,Chen JS,Cai ZG,An JH,Zhang MY,Li Y,Li FP,Hou R,Liu YL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
WDR82-binding long noncoding RNA lncEry controls mouse erythroid differentiation and maturation.
The Journal of experimental medicine
Yang S,Sun G,Wu P,Chen C,Kuang Y,Liu L,Zheng Z,He Y,Gu Q,Lu T,Zhu C,Wang F,Gou F,Yang Z,Zhao X,Yuan S,Yang L,Lu S,Li Y,Lv X,Dong F,Ma Y,Yu J,Ng LG,Shi L,Liu J,Shi L,Cheng T,Cheng H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 04 00:00:00 EDT 2022
Multivalent state transitions shape the intratumoral composition of small cell lung carcinoma.
Science advances
Gopal P,Petty A,Rogacki K,Bera T,Bareja R,Peacock CD,Abazeed ME
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Dec 14 00:00:00 EST 2022
High-Contrast Stimulation Potentiates the Neurotrophic Properties of Müller Cells and Suppresses Their Pro-Inflammatory Phenotype.
International journal of molecular sciences
Zloh M,Kutilek P,Stofkova A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Wed Aug 03 00:00:00 EDT 2022
CXCR4, CXCR5 and CD44 May Be Involved in Homing of Lymphoma Cells into the Eye in a Patient Derived Xenograft Homing Mouse Model for Primary Vitreoretinal Lymphoma.
International journal of molecular sciences
Babst N,Isbell LK,Rommel F,Tura A,Ranjbar M,Grisanti S,Tschuch C,Schueler J,Doostkam S,Reinacher PC,Duyster J,Kakkassery V,von Bubnoff N
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Tue Oct 04 00:00:00 EDT 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Feb 16 00:00:00 EST 2022
RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival.
Cell death & disease
Novak R,Ahmad YA,Timaner M,Bitman-Lotan E,Oknin-Vaisman A,Horwitz R,Hartmann O,Reissland M,Buck V,Rosenfeldt M,Nikomarov D,Diefenbacher ME,Shaked Y,Orian A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Sep 24 00:00:00 EDT 2022
CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2.
Biomedicines
Vadhan A,Hou MF,Vijayaraghavan P,Wu YC,Hu SC,Wang YM,Cheng TL,Wang YY,Yuan SF
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Oct 05 00:00:00 EDT 2022
Circ_RNF13 Regulates the Stemness and Chemosensitivity of Colorectal Cancer by Transcriptional Regulation of DDX27 Mediated by TRIM24 Stabilization.
Cancers
Guo Y,Hu G,Tian B,Ma M,Long F,Chen M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Dec 16 00:00:00 EST 2022
Smad4 and p53 synergize in suppressing autochthonous intestinal cancer.
Cancer medicine
Park JW,Seo MJ,Cho KS,Kook MC,Jeong JM,Roh SG,Cho SY,Cheon JH,Kim HK
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates.
NPJ vaccines
Seenappa LM,Jakubowski A,Steinbuck MP,Palmer E,Haqq CM,Carter C,Fontenot J,Villinger F,McNeil LK,DeMuth PC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis.
Cell reports
Cotton JL,Dang K,Hu L,Sun Y,Singh A,Rajurkar MS,Li Q,Wu X,Mao J
14-0441-82 was used in Immunohistochemistry-immunofluorescence to identify Gli1-expressing mesenchymal cells as a common cell of origin for polyposis associated with PTEN and LKB1 and reveal their engagement of different downstream pathways in gut mesenchyme to suppress gastrointestinal tumorigenesis.
Tue Jul 19 00:00:00 EDT 2022
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq.
Developmental cell
Ulrich ND,Shen YC,Ma Q,Yang K,Hannum DF,Jones A,Machlin J,Randolph JF,Smith YR,Schon SB,Shikanov A,Marsh EE,Lieberman R,Gurczynski SJ,Moore BB,Li JZ,Hammoud S
14-0441-82 was used in Immunohistochemistry to profile 59,738 fallopian tube (FT) cells from four healthy, pre-menopausal subjects.
Mon Apr 11 00:00:00 EDT 2022
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability.
Nature cell biology
Monserrat J,Morales Torres C,Richardson L,Wilson TS,Patel H,Domart MC,Horswell S,Song OR,Jiang M,Crawford M,Bui M,Dalal Y,Scaffidi P
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza.
The Journal of experimental medicine
Rappe JCF,Finsterbusch K,Crotta S,Mack M,Priestnall SL,Wack A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia.
Current biology : CB
Kozawa K,Sekai M,Ohba K,Ito S,Sako H,Maruyama T,Kakeno M,Shirai T,Kuromiya K,Kamasaki T,Kohashi K,Tanaka S,Ishikawa S,Sato N,Asano S,Suzuki H,Tanimura N,Mukai Y,Gotoh N,Tanino M,Tanaka S,Natsuga K,Soga T,Nakamura T,Yabuta Y,Saitou M,Ito T,Matsuura K,Tsunoda M,Kikumori T,Iida T,Mizutani Y,Miyai Y,Kaibuchi K,Enomoto A,Fujita Y
14-0441-82 was used in Western Blotting to suggest that CD44 and COL17A1 are crucial regulators for the clonal expansion of transformed cells within multilayered epithelia, thus being potential targets for early diagnosis and preventive treatment for precancerous lesions.
Mon Jul 26 00:00:00 EDT 2021
Senescent T Cell Induces Brown Adipose Tissue "Whitening" Via Secreting IFN-γ.
Frontiers in cell and developmental biology
Pan XX,Yao KL,Yang YF,Ge Q,Zhang R,Gao PJ,Ruan CC,Wu F
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Mar 23 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
Downregulation of SLC27A6 by DNA Hypermethylation Promotes Proliferation but Suppresses Metastasis of Nasopharyngeal Carcinoma Through Modulating Lipid Metabolism.
Frontiers in oncology
Zhong X,Yang Y,Li B,Liang P,Huang Y,Zheng Q,Wang Y,Xiao X,Mo Y,Zhang Z,Zhou X,Huang G,Zhao W
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jan 21 00:00:00 EST 2022
Thrombospondin-2 spatiotemporal expression in skeletal fractures.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Zondervan RL,Jenkins DC,Reicha JD,Hankenson KD
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
The white matter is a pro-differentiative niche for glioblastoma.
Nature communications
Brooks LJ,Clements MP,Burden JJ,Kocher D,Richards L,Devesa SC,Zakka L,Woodberry M,Ellis M,Jaunmuktane Z,Brandner S,Morrison G,Pollard SM,Dirks PB,Marguerat S,Parrinello S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Mon Apr 12 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Wed Oct 20 00:00:00 EDT 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
In Vitro Anti-cancer Activity of Adipose-Derived Mesenchymal Stem Cells Increased after Infection with Oncolytic Reovirus.
Advanced pharmaceutical bulletin
Babaei A,Bannazadeh Baghi H,Nezhadi A,Jamalpoor Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner.
Cell death & disease
Breuls N,Giarratana N,Yedigaryan L,Garrido GM,Carai P,Heymans S,Ranga A,Deroose C,Sampaolesi M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
miR-34a mimic or pre-mir-34a, which is the better option for cancer therapy? KatoIII as a model to study miRNA action in human gastric cancer cells.
Cancer cell international
Jafari N,Abediankenari S,Hossein-Nataj H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Immuno-Electron and Confocal Laser Scanning Microscopy of the Glycocalyx.
Biology
Twamley SG,Stach A,Heilmann H,Söhl-Kielczynski B,Stangl V,Ludwig A,Münster-Wandowski A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Tue May 04 00:00:00 EDT 2021
Immuno-Electron and Confocal Laser Scanning Microscopy of the Glycocalyx.
Biology
Twamley SG,Stach A,Heilmann H,Söhl-Kielczynski B,Stangl V,Ludwig A,Münster-Wandowski A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Tue May 04 00:00:00 EDT 2021
Immuno-Electron and Confocal Laser Scanning Microscopy of the Glycocalyx.
Biology
Twamley SG,Stach A,Heilmann H,Söhl-Kielczynski B,Stangl V,Ludwig A,Münster-Wandowski A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Tue May 04 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
MiR-125b-5p Is Involved in Sorafenib Resistance through Ataxin-1-Mediated Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma.
Cancers
Hirao A,Sato Y,Tanaka H,Nishida K,Tomonari T,Hirata M,Bando M,Kida Y,Tanaka T,Kawaguchi T,Wada H,Taniguchi T,Okamoto K,Miyamoto H,Muguruma N,Tanahashi T,Takayama T
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression.
iScience
AbuEid M,McAllister DM,McOlash L,Harwig MC,Cheng G,Drouillard D,Boyle KA,Hardy M,Zielonka J,Johnson BD,Hill RB,Kalyanaraman B,Dwinell MB
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Attenuation of apoptotic cell detection triggers thymic regeneration after damage.
Cell reports
Kinsella S,Evandy CA,Cooper K,Iovino L,deRoos PC,Hopwo KS,Granadier DW,Smith CW,Rafii S,Dudakov JA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Protocols for isolation and characterization of mouse placental hemogenic endothelial cells.
STAR protocols
Liang G,Huang B,Wang F,Liu F
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
c-FOS drives reversible basal to squamous cell carcinoma transition.
Cell reports
Kuonen F,Li NY,Haensel D,Patel T,Gaddam S,Yerly L,Rieger K,Aasi S,Oro AE
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Tue Oct 05 00:00:00 EDT 2021
CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells.
iScience
Qadir AS,Guégan JP,Ginestier C,Chaibi A,Bessede A,Charafe-Jauffret E,Macario M,Lavoué V,Rouge TM,Law C,Vilker J,Wang H,Stroup E,Schipma MJ,Bridgeman B,Murmann AE,Ji Z,Legembre P,Peter ME
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Fri Nov 19 00:00:00 EST 2021
3-hydroxyanthranic acid increases the sensitivity of hepatocellular carcinoma to sorafenib by decreasing tumor cell stemness.
Cell death discovery
Gan G,Shi Z,Liu D,Zhang S,Zhu H,Wang Y,Mi J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Jul 06 00:00:00 EDT 2021
A CD10-OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yu S,Lu Y,Su A,Chen J,Li J,Zhou B,Liu X,Xia Q,Li Y,Li J,Huang M,Ye Y,Zhao Q,Jiang S,Yan X,Wang X,Di C,Pan J,Su S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure.
Cell death & disease
Yu H,Yang W,Huang J,Miao X,Wang B,Ren X,Gu Y,Wang Q,Ding X,Guo X,Qian F,Zhang Y,Xu H,Zheng L,Jin M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Dec 16 00:00:00 EST 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Prophylactic efficacy against Mycobacterium tuberculosis using ID93 and lipid-based adjuvant formulations in the mouse model.
PloS one
Baldwin SL,Reese VA,Larsen SE,Beebe E,Guderian J,Orr MT,Fox CB,Reed SG,Coler RN
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Oct 13 00:00:00 EDT 2021
Simvastatin Enhances the Chondrogenesis But Not the Osteogenesis of Adipose-Derived Stem Cells in a Hyaluronan Microenvironment.
Biomedicines
Wu SC,Chang CH,Chang LH,Wu CW,Chen JW,Chen CH,Lin YS,Chang JK,Ho ML
14-0441-82 was used in Binding experiments to indicate that SIM may be an enhancer of HAM-initiated MSC-based chondrogenesis and avoid osteogenesis.
Mon May 17 00:00:00 EDT 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone.
Cell death & disease
He Y,Cheng D,Lian C,Liu Y,Luo W,Wang Y,Ma C,Wu Q,Tian P,He D,Jia Z,Lv X,Zhang X,Pan Z,Lu J,Xiao Y,Zhang P,Liang Y,Yang Q,Hu G
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Neutralization
Thu Sep 23 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells.
Cancer cell
Hu Z,Artibani M,Alsaadi A,Wietek N,Morotti M,Shi T,Zhong Z,Santana Gonzalez L,El-Sahhar S,Carrami EM,Mallett G,Feng Y,Masuda K,Zheng Y,Chong K,Damato S,Dhar S,Campo L,Garruto Campanile R,Soleymani Majd H,Rai V,Maldonado-Perez D,Jones S,Cerundolo V,Sauka-Spengler T,Yau C,Ahmed AA
14-0441-82 was used in Immunohistochemistry (Frozen) to lay the foundation for accurate prognostic and therapeutic stratification of SOC.
Mon Feb 10 00:00:00 EST 2020
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.
Cell metabolism
Angiari S,Runtsch MC,Sutton CE,Palsson-McDermott EM,Kelly B,Rana N,Kane H,Papadopoulou G,Pearce EL,Mills KHG,O'Neill LAJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Feb 04 00:00:00 EST 2020
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
Cell stem cell
Li Q,Sun Y,Jarugumilli GK,Liu S,Dang K,Cotton JL,Xiol J,Chan PY,DeRan M,Ma L,Li R,Zhu LJ,Li JH,Leiter AB,Ip YT,Camargo FD,Luo X,Johnson RL,Wu X,Mao J
14-0441-82 was used in Immunohistochemistry to demonstrate if Lats1/2, the core Hippo kinases, are essential to maintain Wnt pathway activity and intestinal stem cells.
Thu May 07 00:00:00 EDT 2020
Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell responses.
Antiviral research
Matyushenko V,Kotomina T,Kudryavtsev I,Mezhenskaya D,Prokopenko P,Matushkina A,Sivak K,Muzhikyan A,Rudenko L,Isakova-Sivak I
14-0441-82 was used in Flow Cytometry to assess the induction of influenza- and respiratory syncytial virus-specific T cells in response to live attenuated influenza vaccine vector-based vaccination.
Thu Oct 01 00:00:00 EDT 2020
Transfer of metastatic traits via miR-200c in extracellular vesicles derived from colorectal cancer stem cells is inhibited by atractylenolide I.
Clinical and translational medicine
Tang D,Xu X,Ying J,Xie T,Cao G
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Cancer cells educate natural killer cells to a metastasis-promoting cell state.
The Journal of cell biology
Chan IS,Knútsdóttir H,Ramakrishnan G,Padmanaban V,Warrier M,Ramirez JC,Dunworth M,Zhang H,Jaffee EM,Bader JS,Ewald AJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Mon Sep 07 00:00:00 EDT 2020
Cancer cells educate natural killer cells to a metastasis-promoting cell state.
The Journal of cell biology
Chan IS,Knútsdóttir H,Ramakrishnan G,Padmanaban V,Warrier M,Ramirez JC,Dunworth M,Zhang H,Jaffee EM,Bader JS,Ewald AJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Mon Sep 07 00:00:00 EDT 2020
Distinct roles of PIK3CA in the enrichment and maintenance of cancer stem cells in head and neck squamous cell carcinoma.
Molecular oncology
Chen X,Cao Y,Sedhom W,Lu L,Liu Y,Wang H,Oka M,Bornstein S,Said S,Song J,Lu SL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Down-Regulated Exosomal MicroRNA-221 - 3p Derived From Senescent Mesenchymal Stem Cells Impairs Heart Repair.
Frontiers in cell and developmental biology
Sun L,Zhu W,Zhao P,Zhang J,Lu Y,Zhu Y,Zhao W,Liu Y,Chen Q,Zhang F
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Upregulation of Extracellular Vesicles-Encapsulated miR-132 Released From Mesenchymal Stem Cells Attenuates Ischemic Neuronal Injury by Inhibiting Smad2/c-jun Pathway via Acvr2b Suppression.
Frontiers in cell and developmental biology
Feng B,Meng L,Luan L,Fang Z,Zhao P,Zhao G
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that activin receptor type IIB expression is inhibited by miR-132 from mesenchymal stem cells which attenuates ischemic neuronal injury.
Fri Mar 26 00:00:00 EDT 2021
Dexamethasone inhibits stemness maintenance and enhances chemosensitivity of hepatocellular carcinoma stem cells by inducing deSUMOylation of HIF‑1α and Oct4.
International journal of oncology
Jiang Z,Zhang C,Liu X,Ma X,Bian X,Xiao X,Gao R,Sun Y,Wu W,Zhao P
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
Journal of immunology (Baltimore, Md. : 1950)
Bonami RH,Nyhoff LE,McNitt DH,Hulbert C,Felton JL,Kendall PL,Thomas JW
14-0441-82 was used in Flow Cytometry to understand how fully developed T follicular helper cells contribute to different autoimmune processes, investigating the role of signaling lymphocytic activation molecule-associated protein in type 1 diabetes and autoantibody-mediated arthritis.
Tue Dec 15 00:00:00 EST 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
miR‑210 enhances mesenchymal stem cell‑modulated neural precursor cell migration.
Molecular medicine reports
Wang F,Zhu J,Zheng J,Duan W,Zhou Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Identification, characterization and microRNA expression profiling of side population cells in human oral squamous cell carcinoma Tca8113 cell lines.
Molecular medicine reports
Luo W,Liu RS,E LL,Bai Y,Kong XP,Liu HW,Wu H,Liu HC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.
Molecular medicine reports
Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Nanoparticles from Equine Fetal Bone Marrow-Derived Cells Enhance the Survival of Injured Chondrocytes.
Animals : an open access journal from MDPI
Kim KH,Park TS,Cho BW,Kim TM
14-0441-82 was used in Flow Cytometry to study whether fetal bone marrow-derived cells (BMC)-derived nanoparticles can stimulate the survival of equine chondrocytes.
Wed Sep 23 00:00:00 EDT 2020
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.
Nature communications
Azazmeh N,Assouline B,Winter E,Ruppo S,Nevo Y,Maly A,Meir K,Witkiewicz AK,Cohen J,Rizou SV,Pikarsky E,Luxenburg C,Gorgoulis VG,Ben-Porath I
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Mon Jun 01 00:00:00 EDT 2020
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.
Nature communications
Azazmeh N,Assouline B,Winter E,Ruppo S,Nevo Y,Maly A,Meir K,Witkiewicz AK,Cohen J,Rizou SV,Pikarsky E,Luxenburg C,Gorgoulis VG,Ben-Porath I
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Mon Jun 01 00:00:00 EDT 2020
Targeted expression profiling reveals distinct stages of early canine fibroblast reprogramming are regulated by 2-oxoglutarate hydroxylases.
Stem cell research & therapy
Tobias IC,Kao MC,Parmentier T,Hunter H,LaMarre J,Betts DH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Wed Dec 09 00:00:00 EST 2020
Targeted expression profiling reveals distinct stages of early canine fibroblast reprogramming are regulated by 2-oxoglutarate hydroxylases.
Stem cell research & therapy
Tobias IC,Kao MC,Parmentier T,Hunter H,LaMarre J,Betts DH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Wed Dec 09 00:00:00 EST 2020
Diacerein treatment prevents colitis-associated cancer in mice.
World journal of clinical oncology
Paulino DSM,Mendes MCS,Camargo JA,Brambilla SR,Wood Dos Santos T,Ribeiro ML,Carvalheira JBC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Thu Sep 24 00:00:00 EDT 2020
Diacerein treatment prevents colitis-associated cancer in mice.
World journal of clinical oncology
Paulino DSM,Mendes MCS,Camargo JA,Brambilla SR,Wood Dos Santos T,Ribeiro ML,Carvalheira JBC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Thu Sep 24 00:00:00 EDT 2020
Graphene-based 2D constructs for enhanced fibroblast support.
PloS one
Safina I,Bourdo SE,Algazali KM,Kannarpady G,Watanabe F,Vang KB,Biris AS
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Tue Aug 04 00:00:00 EDT 2020
Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening.
Cells
Goričan L,Gole B,Potočnik U
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Jul 16 00:00:00 EDT 2020
Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening.
Cells
Goričan L,Gole B,Potočnik U
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Jul 16 00:00:00 EDT 2020
A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation.
Science advances
Niu L,Lou F,Sun Y,Sun L,Cai X,Liu Z,Zhou H,Wang H,Wang Z,Bai J,Yin Q,Zhang J,Chen L,Peng D,Xu Z,Gao Y,Tang S,Fan L,Wang H
14-0441-82 was used in Flow Cytometry to demonstrate the endogenous existence of a micropeptide encoded by a transcript annotated as "non-protein coding" and characterize a micropeptide as a regulator of antigen presentation and a suppressor of inflammatory diseases.
Fri May 01 00:00:00 EDT 2020
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Effect of Combining Low Temperature Plasma, Negative Pressure Wound Therapy, and Bone Marrow Mesenchymal Stem Cells on an Acute Skin Wound Healing Mouse Model.
International journal of molecular sciences
Cui HS,Joo SY,Cho YS,Park JH,Kim JB,Seo CH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat May 23 00:00:00 EDT 2020
Chemotherapeutic Stress Influences Epithelial-Mesenchymal Transition and Stemness in Cancer Stem Cells of Triple-Negative Breast Cancer.
International journal of molecular sciences
Li X,Strietz J,Bleilevens A,Stickeler E,Maurer J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2020
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Nature communications
Kawabe T,Yi J,Kawajiri A,Hilligan K,Fang D,Ishii N,Yamane H,Zhu J,Jankovic D,Kim KS,Trinchieri G,Sher A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
Inhibition of EZH2 ameliorates bacteria-induced liver injury by repressing RUNX1 in dendritic cells.
Cell death & disease
Wang Y,Wang Q,Wang B,Gu Y,Yu H,Yang W,Ren X,Qian F,Zhao X,Xiao Y,Zhang Y,Jin M,Zhu M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
CD44 cross-linking increases malignancy of breast cancer via upregulation of p-Moesin.
Cancer cell international
Hu S,Shi X,Liu Y,He Y,Du Y,Zhang G,Yang C,Gao F
14-0441-82 was used in Antibody cross-linking to explore whether disruption of CD44 cross-linking in breast cancer cells could prevent the cells migration and invasion and determine the effects of CD44 cross-linking on the malignancy of the cancer cells.
Mon Nov 23 00:00:00 EST 2020
Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer.
Cancers
Witschen PM,Chaffee TS,Brady NJ,Huggins DN,Knutson TP,LaRue RS,Munro SA,Tiegs L,McCarthy JB,Nelson AC,Schwertfeger KL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Nature communications
Toubal A,Kiaf B,Beaudoin L,Cagninacci L,Rhimi M,Fruchet B,da Silva J,Corbett AJ,Simoni Y,Lantz O,Rossjohn J,McCluskey J,Lesnik P,Maguin E,Lehuen A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jul 24 00:00:00 EDT 2020
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.
Science advances
Chao Y,Liang C,Tao H,Du Y,Wu D,Dong Z,Jin Q,Chen G,Xu J,Xiao Z,Chen Q,Wang C,Chen J,Liu Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Utility Evaluation of Porcine Enteroids as PDCoV Infection Model in vitro.
Frontiers in microbiology
Luo H,Zheng J,Chen Y,Wang T,Zhang Z,Shan Y,Xu J,Yue M,Fang W,Li X
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Obesity-Altered Adipose Stem Cells Promote Radiation Resistance of Estrogen Receptor Positive Breast Cancer through Paracrine Signaling.
International journal of molecular sciences
Sabol RA,Villela VA,Denys A,Freeman BT,Hartono AB,Wise RM,Harrison MAA,Sandler MB,Hossain F,Miele L,Bunnell BA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Apr 15 00:00:00 EDT 2020
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Cell death & disease
Huang R,Wang S,Wang N,Zheng Y,Zhou J,Yang B,Wang X,Zhang J,Guo L,Wang S,Chen Z,Wang Z,Xiang S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Apr 16 00:00:00 EDT 2020
Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties.
Cells
Pasquale V,Ducci G,Campioni G,Ventrici A,Assalini C,Busti S,Vanoni M,Vago R,Sacco E
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Dec 11 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation.
Nature biotechnology
Shah NJ,Mao AS,Shih TY,Kerr MD,Sharda A,Raimondo TM,Weaver JC,Vrbanac VD,Deruaz M,Tager AM,Mooney DJ,Scadden DT
14-0441 was used in Flow cytometry/Cell sorting to suggest that bone marrow cryogel, a biomaterial-based scaffold, can be used to enhance T cell immunity after hematopoietic stem cell transplantation.
Fri Mar 01 00:00:00 EST 2019
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Cell
Jin C,Lagoudas GK,Zhao C,Bullman S,Bhutkar A,Hu B,Ameh S,Sandel D,Liang XS,Mazzilli S,Whary MT,Meyerson M,Germain R,Blainey PC,Fox JG,Jacks T
14-0441-82 was used in Flow Cytometry to link local microbiota-immune crosstalk to lung tumor development and thereby define key cellular and molecular mediators that may serve as effective targets in lung cancer intervention.
Thu Feb 21 00:00:00 EST 2019
Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Blood
Albeituni S,Verbist KC,Tedrick PE,Tillman H,Picarsic J,Bassett R,Nichols KE
14-0441-82 was used in Flow Cytometry to show that ruxolitinib operates through IFN-γ-dependent and -independent mechanisms to dampen HLH by targeting the deleterious effects of T cells and neutrophils, with the latter representing an unappreciated and understudied cell type that contributes to HLH pathogenesis.
Thu Jul 11 00:00:00 EDT 2019
A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation.
Circulation research
Lu X,Rudemiller NP,Wen Y,Ren J,Hammer GE,Griffiths R,Privratsky JR,Yang B,Sparks MA,Crowley SD
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Dec 06 00:00:00 EST 2019
High-Molecular-Weight Hyaluronan Is a Hippo Pathway Ligand Directing Cell Density-Dependent Growth Inhibition via PAR1b.
Developmental cell
Ooki T,Murata-Kamiya N,Takahashi-Kanemitsu A,Wu W,Hatakeyama M
14-0441 was used in Immunocytochemistry-immunoflourescence to show that treatment with high-molecular-weight hyaluronan stimulates tumor-suppressive Hippo signaling in breast epithelial cells.
Mon May 20 00:00:00 EDT 2019
A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4+ T and Natural Killer Cells.
Cancer research
Barsoumian HB,Batra L,Shrestha P,Bowen WS,Zhao H,Egilmez NK,Gomez-Gutierrez JG,Yolcu ES,Shirwan H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Feb 15 00:00:00 EST 2019
Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance.
Science signaling
Goldman A,Khiste S,Freinkman E,Dhawan A,Majumder B,Mondal J,Pinkerton AB,Eton E,Medhi R,Chandrasekar V,Rahman MM,Ichimura T,Gopinath KS,Majumder P,Kohandel M,Sengupta S
14-0441-82 was used in Immunocytochemistry to eport that the acquisition of a phenotype marked by increased abundance of CD44 (CD44Hi) by breast cancer cells as a tolerance response to routinely used cytotoxic drugs, such as taxanes, activated a metabolic switch that conferred tolerance against unrelated standard-of-care chemotherapeutic agents, such as anthracyclines.
Tue Aug 20 00:00:00 EDT 2019
Inhibition of T cell activation and function by the adaptor protein CIN85.
Science signaling
Kong MS,Hashimoto-Tane A,Kawashima Y,Sakuma M,Yokosuka T,Kometani K,Onishi R,Carpino N,Ohara O,Kurosaki T,Phua KK,Saito T
14-0441-82 was used in Flow Cytometry to show that CIN85 (Cbl-interacting protein of 85 kDa) limited T cell responses to T cell receptor stimulation.
Tue Feb 05 00:00:00 EST 2019
Clonal copy-number mosaicism in autoreactive T lymphocytes in diabetic NOD mice.
Genome research
Alriyami M,Marchand L,Li Q,Du X,Olivier M,Polychronakos C
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Anisomycin inhibits angiogenesis in ovarian cancer by attenuating the molecular sponge effect of the lncRNA‑Meg3/miR‑421/PDGFRA axis.
International journal of oncology
Ye W,Ni Z,Yicheng S,Pan H,Huang Y,Xiong Y,Liu T
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
Hypoxia changes chemotaxis behaviour of mesenchymal stem cells via HIF-1α signalling.
Journal of cellular and molecular medicine
Xu W,Xu R,Li Z,Wang Y,Hu R
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2019
Pressure-dependent modulation of inward-rectifying K+ channels: implications for cation homeostasis and K+ dynamics in glaucoma.
American journal of physiology. Cell physiology
Fischer RA,Roux AL,Wareham LK,Sappington RM
14-0441 was used in Immunohistochemistry to examine the changes in the expression of inwardly rectifying K+ (Kir) channels and two-pore domain (K2P) channels in response to elevated intraocular pressure (IOP) in vivo and in vitro in primary cultures of Müller glia exposed to elevated hydrostatic pressure.
Thu Aug 01 00:00:00 EDT 2019
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Stem cells international
Sun B,Luo X,Yang C,Liu P,Yang Y,Dong X,Yang Z,Xu J,Zhang Y,Li L
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu May 13 00:00:00 EDT 2021
HMGB3 silence inhibits breast cancer cell proliferation and tumor growth by interacting with hypoxia-inducible factor 1α.
Cancer management and research
Gu J,Xu T,Huang QH,Zhang CM,Chen HY
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.
Molecular medicine reports
Fan C,Ji Q,Zhang C,Xu S,Sun H,Li Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Effects of demographic factors on adipogenic and chondrogenic differentiation in bone marrow-derived stem cells.
Experimental and therapeutic medicine
Lee H,Min SK,Park JB
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway.
EBioMedicine
Seo D,Jung SM,Park JS,Lee J,Ha J,Kim M,Park SH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Better therapeutic potential of bone marrow-derived mesenchymal stem cells compared with chorionic villi-derived mesenchymal stem cells in airway injury model.
Regenerative medicine
Ji S,Wu C,Tong L,Wang L,Zhou J,Chen C,Song Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2019
Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells.
Scientific reports
Hung JJ,Kao YS,Huang CH,Hsu WH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Feb 28 00:00:00 EST 2019
BMX-ARHGAP fusion protein maintains the tumorigenicity of gastric cancer stem cells by activating the JAK/STAT3 signaling pathway.
Cancer cell international
Xu XF,Gao F,Wang JJ,Long C,Chen X,Tao L,Yang L,Ding L,Ji Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Jan 30 00:00:00 EST 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Mar 20 00:00:00 EDT 2019
Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair.
Cell reports
Colunga T,Hayworth M,Kreß S,Reynolds DM,Chen L,Nazor KL,Baur J,Singh AM,Loring JF,Metzger M,Dalton S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Mar 05 00:00:00 EST 2019
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation.
JCI insight
Kono M,Maeda K,Stocton-Gavanescu I,Pan W,Umeda M,Katsuyama E,Burbano C,Orite SYK,Vukelic M,Tsokos MG,Yoshida N,Tsokos GC
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that CaMK4 binds to PKM2 and promotes its activity, which is requisite for Th1 and Th17 differentiation.
Thu Jun 20 00:00:00 EDT 2019
Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection.
Frontiers in immunology
Schreiber M,Weigelt M,Karasinsky A,Anastassiadis K,Schallenberg S,Petzold C,Bonifacio E,Kretschmer K,Hommel A
14-0441 was used in Flow cytometry/Cell sorting to show that transient hyperexpression of IL-7 can impair immune regulation, through disturbances in lymphocyte development pathways, and decrease graft survival time, even under immunosuppression.
Mon Sep 14 00:00:00 EDT 2020
Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells.
Oncoimmunology
Salerno F,Guislain A,Freen-Van Heeren JJ,Nicolet BP,Young HA,Wolkers MC
14-0441 was used in Flow cytometry/Cell sorting to conclude that post-transcriptional mechanisms could be modulated to potentiate effective T cell therapies in cancer.
Tue Jan 12 00:00:00 EST 2021
BRCA1 regulates the cancer stem cell fate of breast cancer cells in the context of hypoxia and histone deacetylase inhibitors.
Scientific reports
Kim H,Lin Q,Yun Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Jul 04 00:00:00 EDT 2019
Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer.
Cancers
Huang JY,Wang YY,Lo S,Tseng LM,Chen DR,Wu YC,Hou MF,Yuan SF
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Dec 20 00:00:00 EST 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Mar 05 00:00:00 EST 2019
Conserved regulation of RNA processing in somatic cell reprogramming.
BMC genomics
Kanitz A,Syed AP,Kaji K,Zavolan M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Jan 31 00:00:00 EST 2019
The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability.
Frontiers in immunology
Ronin E,Lubrano di Ricco M,Vallion R,Divoux J,Kwon HK,Grégoire S,Collares D,Rouers A,Baud V,Benoist C,Salomon BL
14-0441-82 was used in Flow Cytometry to show that RelA, a key member of the NF-κB complex, is critical for Treg biology as it promotes both the generation of their effector phenotype and the maintenance of their identity.
Thu Oct 29 00:00:00 EDT 2020
RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs.
Immunity
Wu B,Zhang S,Guo Z,Wang G,Zhang G,Xie L,Lou J,Chen X,Wu D,Bergmeier W,Zheng J,Wan YY
14-0441 was used in Flow cytometry/Cell sorting to indicate that a distinct molecular program directs pTh17 cell generation and reveals targets for treating pTh17 cell-related pathology and diseases.
Tue Nov 20 00:00:00 EST 2018
The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.
The Journal of experimental medicine
Zhang W,Li Q,Li D,Li J,Aki D,Liu YC
14-0441 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.
Mon Dec 03 00:00:00 EST 2018
Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.
The Journal of experimental medicine
Delpoux A,Michelini RH,Verma S,Lai CY,Omilusik KD,Utzschneider DT,Redwood AJ,Goldrath AW,Benedict CA,Hedrick SM
14-0441 was used in Flow cytometry/Cell sorting to show that FOXO1 is continuously required for all the phenotypic characteristics of memory-effector T cells.
Mon Feb 05 00:00:00 EST 2018
IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes.
The Journal of experimental medicine
Yang J,Cornelissen F,Papazian N,Reijmers RM,Llorian M,Cupedo T,Coles M,Seddon B
14-0441 was used in Flow cytometry/Cell sorting to investigate whether continued IL-7 expression was required for the maintenance of fully developed, adult lymph nodes.
Mon Apr 02 00:00:00 EDT 2018
Small-Molecule Inhibition of PD-1 Transcription Is an Effective Alternative to Antibody Blockade in Cancer Therapy.
Cancer research
Taylor A,Rothstein D,Rudd CE
14-0441 was used in Flow cytometry/Cell sorting to show how GSK-3 inhibitors that downregulate PD-1 expression can enhance CD8+ T-cell function in cancer therapy to a similar degree as PD-1 blocking antibodies, offering a next-generation approach in the design of immunotherapeutic approaches for cancer management.
Thu Feb 01 00:00:00 EST 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.
Oncogene
Solomon H,Dinowitz N,Pateras IS,Cooks T,Shetzer Y,Molchadsky A,Charni M,Rabani S,Koifman G,Tarcic O,Porat Z,Kogan-Sakin I,Goldfinger N,Oren M,Harris CC,Gorgoulis VG,Rotter V
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions.
Mucosal immunology
Varanasi SK,Rajasagi NK,Jaggi U,Rouse BT
14-0441 was used in Flow cytometry/Cell sorting to investigate IL-18's mechanisms to control of inflammatory lesions in the cornea caused by the herpes infection.
Thu Nov 01 00:00:00 EDT 2018
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.
Breast cancer research : BCR
Kim H,Lin Q,Glazer PM,Yun Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Mar 06 00:00:00 EST 2018
SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer.
The Journal of cell biology
Viotti M,Wilson C,McCleland M,Koeppen H,Haley B,Jhunjhunwala S,Klijn C,Modrusan Z,Arnott D,Classon M,Stephan JP,Mellman I
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2018
Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells.
Journal of immunology (Baltimore, Md. : 1950)
Ferdinand JR,Richard AC,Meylan F,Al-Shamkhani A,Siegel RM
14-0441 was used in Flow cytometry/Cell sorting to suggest differential roles for membrane and soluble TL1A on adaptive and innate immune cells and have implications for the consequences of blocking these two forms of TL1A.
Thu Feb 15 00:00:00 EST 2018
IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4+ T Cell Migration.
Journal of immunology (Baltimore, Md. : 1950)
Smith CJ,Allard DE,Wang Y,Howard JF,Montgomery SA,Su MA
14-0441 was used in Flow cytometry/Cell sorting to delineate a novel mechanism in which IL-10-induced STAT3 increases S1pr1 expression and CD4+ T cell migration to accelerate T cell-mediated destruction of peripheral nerves.
Thu Mar 01 00:00:00 EST 2018
STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Majri SS,Fritz JM,Villarino AV,Zheng L,Kanellopoulou C,Chaigne-Delalande B,Grönholm J,Niemela JE,Afzali B,Biancalana M,Pittaluga S,Sun A,Cohen JL,Holland SM,O'Shea JJ,Uzel G,Lenardo MJ
14-0441 was used in Flow cytometry/Cell sorting to show that STAT5B, a transcription factor downstream of multiple cytokines involved in RICD, is essential for triggering apoptosis of mouse and human TEM cells, and that altered STAT5B transcriptional activity drives immunodeficiency and dysfunction.
Mon Jan 01 00:00:00 EST 2018
A correlation study of the expression of HA-CD44st and HER-2 in breast cancer.
OncoTargets and therapy
Ying Zhi L,Xu Z,Ning L,Jia Jin L,Hai Cui Y,Hong HG,Fang XJ
14-0441 was used in Functional assays to investigate the effect of hyaluronic acid-CD44st on the invasive ability of human breast cancer MCF-7 cells.
Thu Mar 31 00:00:00 EDT 2022
Polymethoxylated Flavones from Orange Peels Inhibit Cell Proliferation in a 3D Cell Model of Human Colorectal Cancer.
Nutrition and cancer
Silva I,Estrada MF,V Pereira C,da Silva AB,Bronze MR,Alves PM,Duarte CMM,Brito C,Serra AT
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunocytochemistry
Wed Apr 03 00:00:00 EDT 2019
Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43.
Experimental and therapeutic medicine
Li Z,Zhang S,Cao L,Li W,Ye YC,Shi ZX,Wang ZR,Sun LX,Wang JW,Jia LT,Wang W
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients.
Journal of experimental & clinical cancer research : CR
Zhang J,Cai H,Sun L,Zhan P,Chen M,Zhang F,Ran Y,Wan J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Wed Sep 12 00:00:00 EDT 2018
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin.
Oncotarget
Huang W,Bei L,Eklund EA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 25 00:00:00 EDT 2018
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer.
eLife
Li J,Choi PS,Chaffer CL,Labella K,Hwang JH,Giacomelli AO,Kim JW,Ilic N,Doench JG,Ly SH,Dai C,Hagel K,Hong AL,Gjoerup O,Goel S,Ge JY,Root DE,Zhao JJ,Brooks AN,Weinberg RA,Hahn WC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jul 30 00:00:00 EDT 2018
TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival.
Nature communications
Zhu L,Xie X,Zhang L,Wang H,Jie Z,Zhou X,Shi J,Zhao S,Zhang B,Cheng X,Sun SC
14-0441 was used in Flow cytometry/Cell sorting to study the mechanism of IL-15 function in autophagy and natural killer cell survival.
Wed Jul 18 00:00:00 EDT 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation.
Cell reports
Chiou NT,Kageyama R,Ansel KM
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Dec 18 00:00:00 EST 2018
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Cancer cell
Turaj AH,Hussain K,Cox KL,Rose-Zerilli MJJ,Testa J,Dahal LN,Chan HTC,James S,Field VL,Carter MJ,Kim HJ,West JJ,Thomas LJ,He LZ,Keler T,Johnson PWM,Al-Shamkhani A,Thirdborough SM,Beers SA,Cragg MS,Glennie MJ,Lim SH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Dec 11 00:00:00 EST 2017
The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.
Nature immunology
Shan Q,Zeng Z,Xing S,Li F,Hartwig SM,Gullicksrud JA,Kurup SP,Van Braeckel-Budimir N,Su Y,Martin MD,Varga SM,Taniuchi I,Harty JT,Peng W,Badovinac VP,Xue HH
14-0441 was used in Flow cytometry/Cell sorting to show that Runx3-mediated Tcf7 repression coordinately enforced acquisition of cytotoxic functions and protected the cytotoxic lineage integrity by preventing TFH-lineage deviation.
Tue Aug 01 00:00:00 EDT 2017
Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.
Cell stem cell
Ruetz T,Pfisterer U,Di Stefano B,Ashmore J,Beniazza M,Tian TV,Kaemena DF,Tosti L,Tan W,Manning JR,Chantzoura E,Ottosson DR,Collombet S,Johnsson A,Cohen E,Yusa K,Linnarsson S,Graf T,Parmar M,Kaji K
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Dec 07 00:00:00 EST 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Xu X,Han L,Zhao G,Xue S,Gao Y,Xiao J,Zhang S,Chen P,Wu ZY,Ding J,Hu R,Wei B,Wang H
14-0441 was used in Flow cytometry/Cell sorting to demonstrate LRCH1 as a novel effector to restrain PKCα-DOCK8-Cdc42 module-induced T cell migration and ameliorate EAE.
Sun Jan 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity.
The Journal of experimental medicine
Chen S,Cai C,Li Z,Liu G,Wang Y,Blonska M,Li D,Du J,Lin X,Yang M,Dong Z
14-0441-82 was used in Flow Cytometry to examine NKT cell development and humoral immunity in mice completely deficient in SFR.
Wed Feb 01 00:00:00 EST 2017
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America
Bierie B,Pierce SE,Kroeger C,Stover DG,Pattabiraman DR,Thiru P,Liu Donaher J,Reinhardt F,Chaffer CL,Keckesova Z,Weinberg RA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms.
Proceedings of the National Academy of Sciences of the United States of America
Briseño CG,Gargaro M,Durai V,Davidson JT,Theisen DJ,Anderson DA,Novack DV,Murphy TL,Murphy KM
14-0441 was used in Flow cytometry/Cell sorting to suggest that there is an unrecognized but critical role for RelB within the nonhematopoietic niche that controls normal myelopoiesis.
Tue Apr 11 00:00:00 EDT 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-0441-82 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 EDT 2017
NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation.
European journal of immunology
Miletic A,Lenartic M,Popovic B,Brizic I,Trsan T,Miklic K,Mandelboim O,Krmpotic A,Jonjic S
14-0441 was used in Flow cytometry/Cell sorting to provide evidence for the role of NCR1 in antibody response to mouse cytomegalovirus infection.
Fri Sep 01 00:00:00 EDT 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes.
Journal of immunology (Baltimore, Md. : 1950)
Horvatinovich JM,Grogan EW,Norris M,Steinkasserer A,Lemos H,Mellor AL,Tcherepanova IY,Nicolette CA,DeBenedette MA
14-0441 was used in Flow cytometry/Cell sorting to investigate the mechanism of action underlying the tolerogenic function of soluble CD83.
Wed Mar 15 00:00:00 EDT 2017
IL-1β-induces NF-κB and upregulates microRNA-372 to inhibit spinal cord injury recovery.
Journal of neurophysiology
Zhou W,Yuan T,Gao Y,Yin P,Liu W,Pan C,Liu Y,Yu X
14-0441 was used in Flow cytometry/Cell sorting to study the role of miR-372 in inflammatory signalling in spinal cord injury.
Thu Jun 01 00:00:00 EDT 2017
A high-yield isolation and enrichment strategy for human lung microvascular endothelial cells.
Pulmonary circulation
Gaskill C,Majka SM
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Comparison of Four Protocols to Generate Chondrocyte-Like Cells from Human Induced Pluripotent Stem Cells (hiPSCs).
Stem cell reviews and reports
Suchorska WM,Augustyniak E,Richter M,Trzeciak T
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
A robust in vitro model for trans-lymphatic endothelial migration.
Scientific reports
Xiong Y,Brinkman CC,Famulski KS,Mongodin EF,Lord CJ,Hippen KL,Blazar BR,Bromberg JS
14-0441 was used in Flow cytometry/Cell sorting to establish an in vitro system to evaluate lymphatic Trans-endothelial migration for various cell types across primary mouse and human lymphatic endothelial cells.
Tue May 09 00:00:00 EDT 2017
Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.
Scientific reports
Alzubi J,Pallant C,Mussolino C,Howe SJ,Thrasher AJ,Cathomen T
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Sep 29 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model.
Oncoimmunology
Field CS,Hunn MK,Ferguson PM,Ruedl C,Ancelet LR,Hermans IF
14-0441 was used in Flow cytometry/Cell sorting to study the effect of the checkpoint blockade on the efficacy of responses induced with a whole tumour-cell vaccine.
Tue Jan 12 00:00:00 EST 2021
Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling.
Theranostics
Cao Y,Lin SH,Wang Y,Chin YE,Kang L,Mi J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 30 00:00:00 EDT 2018
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
JCI insight
Le Saout C,Luckey MA,Villarino AV,Smith M,Hasley RB,Myers TG,Imamichi H,Park JH,O'Shea JJ,Lane HC,Catalfamo M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Nov 16 00:00:00 EST 2017
HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival.
Cell death & disease
Lacher SM,Bruttger J,Kalt B,Berthelet J,Rajalingam K,Wörtge S,Waisman A
14-0441 was used in Flow cytometry/Cell sorting to show that protein prenylation rather than cholesterol biosynthesis pathway is indispensible for T-cell survival.
Thu May 25 00:00:00 EDT 2017
SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction.
Oncotarget
Gao Z,Jin YQ,Wu W
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue May 16 00:00:00 EDT 2017
CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model.
Oncoimmunology
Gebauer C,Pignolet B,Yshii L,Mauré E,Bauer J,Liblau R
14-0441 was used in Flow cytometry/Cell sorting to provide further insight into the cellular mechanisms whereby a potent anti-tumor immunity triggers a cancer-associated autoimmune disease, and may therefore help to develop new therapeutic strategies against PND.
Tue Jan 12 00:00:00 EST 2021
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Nature genetics
Jabara HH,Boyden SE,Chou J,Ramesh N,Massaad MJ,Benson H,Bainter W,Fraulino D,Rahimov F,Sieff C,Liu ZJ,Alshemmari SH,Al-Ramadi BK,Al-Dhekri H,Arnaout R,Abu-Shukair M,Vatsayan A,Silver E,Ahuja S,Davies EG,Sola-Visner M,Ohsumi TK,Andrews NC,Notarangelo LD,Fleming MD,Al-Herz W,Kunkel LM,Geha RS
14-0441 was used in Flow cytometry/Cell sorting to demonstrate the importance of TfR1 in adaptive immunity.
Fri Jan 01 00:00:00 EST 2016
Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.
Nature immunology
Xing S,Li F,Zeng Z,Zhao Y,Yu S,Shan Q,Li Y,Phillips FC,Maina PK,Qi HH,Liu C,Zhu J,Pope RM,Musselman CA,Zeng C,Peng W,Xue HH
14-0441 was used in Flow cytometry/Cell sorting to reveal that sequence-specific transcription factors can utilise intrinsic HDAC activity to guard cell identity by repressing lineage-inappropriate genes.
Wed Jun 01 00:00:00 EDT 2016
A septin requirement differentiates autonomous and contact-facilitated T cell proliferation.
Nature immunology
Mujal AM,Gilden JK,Gérard A,Kinoshita M,Krummel MF
14-0441 was used in Functional assays to characterise T cells lacking the septin cytoskeleton.
Tue Mar 01 00:00:00 EST 2016
A septin requirement differentiates autonomous and contact-facilitated T cell proliferation.
Nature immunology
Mujal AM,Gilden JK,Gérard A,Kinoshita M,Krummel MF
14-0441 was used in Functional assays to characterise T cells lacking the septin cytoskeleton.
Tue Mar 01 00:00:00 EST 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression.
The Journal of clinical investigation
Patterson SJ,Pesenacker AM,Wang AY,Gillies J,Mojibian M,Morishita K,Tan R,Kieffer TJ,Verchere CB,Panagiotopoulos C,Levings MK
14-0441-82 was used in Flow Cytometry to investigate how Treg-to-target proximity is controlled.
Tue Mar 01 00:00:00 EST 2016
SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.
PLoS biology
Kim BR,Van de Laar E,Cabanero M,Tarumi S,Hasenoeder S,Wang D,Virtanen C,Suzuki T,Bandarchi B,Sakashita S,Pham NA,Lee S,Keshavjee S,Waddell TK,Tsao MS,Moghal N
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells.
Oncogene
Tang W,Wang H,Ha HL,Tassi I,Bhardwaj R,Claudio E,Siebenlist U
14-0441 was used in Flow cytometry/Cell sorting to study the role of Bcl-3 in AOM/DSS induced colon tumours.
Thu Dec 01 00:00:00 EST 2016
Stem Cells Antigen-1 Enriches for a Cancer Stem Cell-Like Subpopulation in Mouse Gastric Cancer.
Stem cells (Dayton, Ohio)
Park JW,Park JM,Park DM,Kim DY,Kim HK
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Differential Responsiveness of Innate-like IL-17- and IFN-γ-Producing γδ T Cells to Homeostatic Cytokines.
Journal of immunology (Baltimore, Md. : 1950)
Corpuz TM,Stolp J,Kim HO,Pinget GV,Gray DH,Cho JH,Sprent J,Webster KE
14-0441 was used in Flow cytometry/Cell sorting to suggest that γδ T cell subsets do not directly compete with each other for cytokines, but instead fall into resource niches with other functionally similar lymphocytes.
Fri Jan 15 00:00:00 EST 2016
Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Jones LL,Alli R,Li B,Geiger TL
14-0441 was used in Flow cytometry/Cell sorting to demonstrate a key role for the regulation of receptor expression in differentiating the functional outcomes of IL-6 and IL-10 signalling.
Fri Apr 01 00:00:00 EDT 2016
Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.
Molecular medicine reports
Shao J,Fan W,Ma B,Wu Y
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunofluorescence
Thu Dec 01 00:00:00 EST 2016
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Molecular medicine reports
Hu Y,Zhang Y,Tian K,Xun C,Wang S,Lv D
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Comparable roles of CD44v8-10 and CD44s in the development of bone metastases in a mouse model.
Oncology letters
Hiraga T,Nakamura H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression.
Oncology letters
Zhang Y,Cabarcas SM,Zheng JI,Sun L,Mathews LA,Zhang X,Lin H,Farrar WL
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells.
Iranian journal of basic medical sciences
Monfared MH,Minaee B,Rastegar T,Khrazinejad E,Barbarestani M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates.
Stem cell reports
Quattrocelli M,Giacomazzi G,Broeckx SY,Ceelen L,Bolca S,Spaas JH,Sampaolesi M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunofluorescence
Tue Jan 12 00:00:00 EST 2016
Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates.
Stem cell reports
Quattrocelli M,Giacomazzi G,Broeckx SY,Ceelen L,Bolca S,Spaas JH,Sampaolesi M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunofluorescence
Tue Jan 12 00:00:00 EST 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration.
Nature communications
Brinkman CC,Iwami D,Hritzo MK,Xiong Y,Ahmad S,Simon T,Hippen KL,Blazar BR,Bromberg JS
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Jun 21 00:00:00 EDT 2016
The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states.
BMC biology
Toneff MJ,Sreekumar A,Tinnirello A,Hollander PD,Habib S,Li S,Ellis MJ,Xin L,Mani SA,Rosen JM
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jun 17 00:00:00 EDT 2016
CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.
PloS one
Huang B,Gomez-Rodriguez J,Preite S,Garrett LJ,Harper UL,Schwartzberg PL
14-0441 was used in Flow cytometry/Cell sorting to elucidate the contribution of the SLAM receptors in immunodysregulation observed in X-linked lymphoproliferative syndrome Type 1.
Mon Jul 24 00:00:00 EDT 2017
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy.
Nature communications
Griffiths KL,Ahmed M,Das S,Gopal R,Horne W,Connell TD,Moynihan KD,Kolls JK,Irvine DJ,Artyomov MN,Rangel-Moreno J,Khader SA
14-0441 was used in Flow cytometry/Cell sorting to demonstrate a novel method of pulmonary vaccine delivery using antigen-primed DCs for Tuberculosis infection.
Thu Dec 22 00:00:00 EST 2016
Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production.
Stem cell research & therapy
Camilleri ET,Gustafson MP,Dudakovic A,Riester SM,Garces CG,Paradise CR,Takai H,Karperien M,Cool S,Sampen HJ,Larson AN,Qu W,Smith J,Dietz AB,van Wijnen AJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Aug 11 00:00:00 EDT 2016
Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent.
PloS one
Morabito KM,Erez N,Graham BS,Ruckwardt TJ
14-0441 was used in Flow cytometry/Cell sorting to compare the immune response to respiratory syncytial virus infection following adoptive transfer of two transgenic CD8+ T cell lines.
Tue Jul 19 00:00:00 EDT 2016
Conditions for the generation of cytotoxic CD4(+) Th cells that enhance CD8(+) CTL-mediated tumor regression.
Clinical & translational immunology
Li K,Baird M,Yang J,Jackson C,Ronchese F,Young S
14-0441 was used in Flow cytometry/Cell sorting to provide valuable data for further research into in vitro expansion of CD4(+) Th1-like cells, with potential applications to cancer treatment involving ACT.
Mon Aug 01 00:00:00 EDT 2016
CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation.
Nature communications
Cao W,Guo J,Wen X,Miao L,Lin F,Xu G,Ma R,Yin S,Hui Z,Chen T,Guo S,Chen W,Huang Y,Liu Y,Wang J,Wei L,Wang L
14-0441 was used in Flow cytometry/Cell sorting to investigate whether the CpG-binding protein Cxxc1 plays a role in thymocyte development.
Mon May 23 00:00:00 EDT 2016
Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells.
PLoS genetics
Lomada D,Jain M,Bolner M,Reeh KA,Kang R,Reddy MC,DiGiovanni J,Richie ER
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that in addition to the NFkB pathway, Stat3-mediated signals play an essential role in regulating mTEC cellularity and medullary region homeostasis.
Fri Jan 01 00:00:00 EST 2016
Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration.
Oncotarget
Greenwood E,Maisel S,Ebertz D,Russ A,Pandey R,Schroeder J
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Sep 20 00:00:00 EDT 2016
Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction.
Nature communications
Cruz AC,Ramaswamy M,Ouyang C,Klebanoff CA,Sengupta P,Yamamoto TN,Meylan F,Thomas SK,Richoz N,Eil R,Price S,Casellas R,Rao VK,Lippincott-Schwartz J,Restifo NP,Siegel RM
14-0441 was used in Flow cytometry/Cell sorting to elucidate how palmitoylation defects in the Fas/CD95 receptor impact primary immune cells.
Fri Dec 23 00:00:00 EST 2016
PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes.
Immunoendocrinology (Houston, Tex.)
Martinov T,Spanier JA,Pauken KE,Fife BT
14-0441 was used in Flow cytometry/Cell sorting to understand the role of PD-1 in maintaining islet-specific tolerance in diabetes-resistant strains.
Wed Mar 30 00:00:00 EDT 2022
Tumor Progression Locus 2 (Tpl2) Activates the Mammalian Target of Rapamycin (mTOR) Pathway, Inhibits Forkhead Box P3 (FoxP3) Expression, and Limits Regulatory T Cell (Treg) Immunosuppressive Functions.
The Journal of biological chemistry
Li X,Acuff NV,Peeks AR,Kirkland R,Wyatt KD,Nagy T,Watford WT
14-0441-82 was used in Flow Cytometry to demonstrate that the serine/threonine kinase tumour progression locus 2 constrains the development of inducible regulatory T cells.
Fri Aug 05 00:00:00 EDT 2016
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Nature biotechnology
Chen HJ,Sun J,Huang Z,Hou H,Arcilla M,Rakhilin N,Joe DJ,Choi J,Gadamsetty P,Milsom J,Nandakumar G,Longman R,Zhou XK,Edwards R,Chen J,Chen KY,Bu P,Wang L,Xu Y,Munroe R,Abratte C,Miller AD,Gümüş ZH,Shuler M,Nishimura N,Edelmann W,Shen X,Lipkin SM
14-0441 was used in Flow cytometry/Cell sorting to create chemokine-targeted mouse models that recapitulate the majority of common human somatic CRC mutations.
Mon Jun 01 00:00:00 EDT 2015
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Nature immunology
Finkin S,Yuan D,Stein I,Taniguchi K,Weber A,Unger K,Browning JL,Goossens N,Nakagawa S,Gunasekaran G,Schwartz ME,Kobayashi M,Kumada H,Berger M,Pappo O,Rajewsky K,Hoshida Y,Karin M,Heikenwalder M,Ben-Neriah Y,Pikarsky E
14-0441 was used in Immunofluorescence-paraffin to reveal the function of ectopic lymphoid-like structures in cancer.
Tue Dec 01 00:00:00 EST 2015
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Nature immunology
Finkin S,Yuan D,Stein I,Taniguchi K,Weber A,Unger K,Browning JL,Goossens N,Nakagawa S,Gunasekaran G,Schwartz ME,Kobayashi M,Kumada H,Berger M,Pappo O,Rajewsky K,Hoshida Y,Karin M,Heikenwalder M,Ben-Neriah Y,Pikarsky E
14-0441 was used in Immunofluorescence-paraffin to reveal the function of ectopic lymphoid-like structures in cancer.
Tue Dec 01 00:00:00 EST 2015
LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.
Nature immunology
Choi YS,Gullicksrud JA,Xing S,Zeng Z,Shan Q,Li F,Love PE,Peng W,Xue HH,Crotty S
14-0441 was used in Flow cytometry/Cell sorting to report that selective loss of Lef1 or Tcf7 results in T(FH) cell defects.
Tue Sep 01 00:00:00 EDT 2015
Anisotropic stress orients remodelling of mammalian limb bud ectoderm.
Nature cell biology
Lau K,Tao H,Liu H,Wen J,Sturgeon K,Sorfazlian N,Lazic S,Burrows JT,Wong MD,Li D,Deimling S,Ciruna B,Scott I,Simmons C,Henkelman RM,Williams T,Hadjantonakis AK,Fernandez-Gonzalez R,Sun Y,Hopyan S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunofluorescence
Fri May 01 00:00:00 EDT 2015
Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle.
The Journal of clinical investigation
Quattrocelli M,Swinnen M,Giacomazzi G,Camps J,Barthélemy I,Ceccarelli G,Caluwé E,Grosemans H,Thorrez L,Pelizzo G,Muijtjens M,Verfaillie CM,Blot S,Janssens S,Sampaolesi M
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Bcl11b is essential for group 2 innate lymphoid cell development.
The Journal of experimental medicine
Walker JA,Oliphant CJ,Englezakis A,Yu Y,Clare S,Rodewald HR,Belz G,Liu P,Fallon PG,McKenzie AN
14-0441 was used in Flow cytometry/Cell sorting to study the role of Bcl11b in the differentiation of group 2 innate lymphoid cells.
Mon Jun 01 00:00:00 EDT 2015
Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection.
The Journal of experimental medicine
Omilusik KD,Best JA,Yu B,Goossens S,Weidemann A,Nguyen JV,Seuntjens E,Stryjewska A,Zweier C,Roychoudhuri R,Gattinoni L,Bird LM,Higashi Y,Kondoh H,Huylebroeck D,Haigh J,Goldrath AW
14-0441-82 was used in Flow Cytometry to study the upregulation of ZEB2 by activated T cells, specifically in the KLRG1(hi) effector CD8(+) T cell subset.
Mon Nov 16 00:00:00 EST 2015
Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo.
Science advances
Hoffmann MM,Molina-Mendiola C,Nelson AD,Parks CA,Reyes EE,Hansen MJ,Rajagopalan G,Pease LR,Schrum AG,Gil D
14-0441 was used in Flow cytometry/Cell sorting to investigate co-potentiation, showing that weak T-cell responses can be boosted to provide immunotherapy in vivo.
Thu Oct 01 00:00:00 EDT 2015
Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.
Cancer research
Zhang S,Chung WC,Wu G,Egan SE,Miele L,Xu K
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.
Genes & development
Miyazaki M,Miyazaki K,Chen S,Chandra V,Wagatsuma K,Agata Y,Rodewald HR,Saito R,Chang AN,Varki N,Kawamoto H,Murre C
14-0441 was used in Flow cytometry/Cell sorting to show that Id2 and Id3 suppress the development and expansion of innate variant follicular helper T cells.
Sun Feb 15 00:00:00 EST 2015
LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.
EMBO reports
Walsh NC,Waters LR,Fowler JA,Lin M,Cunningham CR,Brooks DG,Rehg JE,Morse HC,Teitell MA
14-0441 was used in Flow cytometry/Cell sorting to show that LKB1 expression in B cells maintains B-cell quiescence and prevents the premature formation of germinal centers.
Mon Jun 01 00:00:00 EDT 2015
Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice.
Mucosal immunology
Bertin S,Lozano-Ruiz B,Bachiller V,García-Martínez I,Herdman S,Zapater P,Francés R,Such J,Lee J,Raz E,González-Navajas JM
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that DUSP6 regulates CD4+ T-cell activation and differentiation by inhibiting TCR-dependent ERK1/2 activation.
Fri May 01 00:00:00 EDT 2015
IL-4 Induced Innate CD8+ T Cells Control Persistent Viral Infection.
PLoS pathogens
Lee A,Park SP,Park CH,Kang BH,Park SH,Ha SJ,Jung KC
14-0441 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-4-induced innate CD8+ T cells control chronic virus infection.
Thu Oct 01 00:00:00 EDT 2015
Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.
PLoS pathogens
Nanjappa SG,Hernández-Santos N,Galles K,Wüthrich M,Suresh M,Klein BS
14-0441 was used in Flow cytometry/Cell sorting to show that T cell-intrinsic MyD88 signals are crucial for these Tc17 cell responses and vaccine immunity against lethal fungal pneumonia in mice.
Tue Sep 01 00:00:00 EDT 2015
γδ T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice.
Journal of leukocyte biology
Mehta P,Nuotio-Antar AM,Smith CW
14-0441 was used in Flow cytometry/Cell sorting to reveal that isolated γδ T cells directly stimulated RAW264.7 macrophage TNF-α expression but did not stimulate inflammatory mediator expression in 3T3-L1 adipocytes.
Thu Jan 01 00:00:00 EST 2015
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Grinberg-Bleyer Y,Dainichi T,Oh H,Heise N,Klein U,Schmid RM,Hayden MS,Ghosh S
14-0441-82 was used in Flow Cytometry to analyse the function of canonical NF-κB in the epidermis using CRE-mediated deletion of p65 and c-Rel in keratinocytes.
Sun Mar 15 00:00:00 EDT 2015
PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950)
Pearce VQ,Bouabe H,MacQueen AR,Carbonaro V,Okkenhaug K
14-0441 was used in Flow cytometry/Cell sorting to investigate the effect of inhibition of the p110δ subunit of PI3Kδ on CD8(+) T cell responses to Listeria monocytogenes infection.
Thu Oct 01 00:00:00 EDT 2015
PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Park HJ,Park JS,Jeong YH,Son J,Ban YH,Lee BH,Chen L,Chang J,Chung DH,Choi I,Ha SJ
14-0441 was used in Flow cytometry/Cell sorting to define PD-1 upregulated on Treg cells and its interaction with PD-1 ligand on effector T cells as one cause for the potent T cell suppression.
Mon Jun 15 00:00:00 EDT 2015
Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45.
Human vaccines & immunotherapeutics
Vijayachari P,Vedhagiri K,Mallilankaraman K,Mathur PP,Sardesai NY,Weiner DB,Ugen KE,Muthumani K
14-0441 was used in Flow cytometry/Cell sorting to test the efficacy of a synthetic consensus DNA vaccine developed against the Leptospira membrane lipoprotein LipL45, demonstrating that this LipL45 based DNA immunogen has potential as a anti-Leptospira vaccine.
Wed May 04 00:00:00 EDT 2016
Enrichment of Human Stem-Like Prostate Cells with s-SHIP Promoter Activity Uncovers a Role in Stemness for the Long Noncoding RNA H19.
Stem cells and development
Bauderlique-Le Roy H,Vennin C,Brocqueville G,Spruyt N,Adriaenssens E,Bourette RP
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
Special AT-rich sequence-binding protein-1 participates in the maintenance of breast cancer stem cells through regulation of the Notch signaling pathway and expression of Snail1 and Twist1.
Molecular medicine reports
Sun Z,Zhang C,Zou X,Jiang G,Xu Z,Li W,Xie H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Multi-lineage differentiation of human umbilical cord Wharton's Jelly Mesenchymal Stromal Cells mediates changes in the expression profile of stemness markers.
PloS one
Ali H,Al-Yatama MK,Abu-Farha M,Behbehani K,Al Madhoun A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Western Blot
Fri Mar 25 00:00:00 EDT 2016
Multi-lineage differentiation of human umbilical cord Wharton's Jelly Mesenchymal Stromal Cells mediates changes in the expression profile of stemness markers.
PloS one
Ali H,Al-Yatama MK,Abu-Farha M,Behbehani K,Al Madhoun A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Western Blot
Fri Mar 25 00:00:00 EDT 2016
Multi-lineage differentiation of human umbilical cord Wharton's Jelly Mesenchymal Stromal Cells mediates changes in the expression profile of stemness markers.
PloS one
Ali H,Al-Yatama MK,Abu-Farha M,Behbehani K,Al Madhoun A
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Western Blot
Fri Mar 25 00:00:00 EDT 2016
Reprogramming Roadblocks Are System Dependent.
Stem cell reports
Chantzoura E,Skylaki S,Menendez S,Kim SI,Johnsson A,Linnarsson S,Woltjen K,Chambers I,Kaji K
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
Memory T cells generated by prior exposure to influenza cross react with the novel H7N9 influenza virus and confer protective heterosubtypic immunity.
PloS one
McMaster SR,Gabbard JD,Koutsonanos DG,Compans RW,Tripp RA,Tompkins SM,Kohlmeier JE
14-0441 was used in Flow cytometry/Cell sorting to quantify the H7N9 cross-reactive memory T cell reservoir in humans and mice previously exposed to common circulating influenza viruses.
Tue Jan 19 00:00:00 EST 2016
Label-free detection of rare cell in human blood using gold nano slit surface plasmon resonance.
Biosensors
Mousavi MZ,Chen HY,Hou HS,Chang CY,Roffler S,Wei PK,Cheng JY
14-0441 was used in Binding experiments to develop a method of label-free detection of rare cells in biological samples using Surface Plasmon Resonance.
Mon Mar 23 00:00:00 EDT 2015
Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6.
Oncotarget
Andersson KM,Brisslert M,Cavallini NF,Svensson MN,Welin A,Erlandsson MC,Ciesielski MJ,Katona G,Bokarewa MI
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that survivin ensures optimal function of follicular T-cells by regulating transcriptional activity of Bcl-6.
Fri Aug 21 00:00:00 EDT 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2015
Interleukin-35 administration counteracts established murine type 1 diabetes--possible involvement of regulatory T cells.
Scientific reports
Singh K,Kadesjö E,Lindroos J,Hjort M,Lundberg M,Espes D,Carlsson PO,Sandler S,Thorvaldson L
14-0441 was used in Flow cytometry/Cell sorting to suggest that insufficient IL-35 levels play a pivotal role in the development of T1D and that treatment with IL-35 should be investigated in treatment of T1D and other autoimmune diseases.
Thu Jul 30 00:00:00 EDT 2015
Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model.
Stem cell research & therapy
Zhou F,Gao S,Wang L,Sun C,Chen L,Yuan P,Zhao H,Yi Y,Qin Y,Dong Z,Cao L,Ren H,Zhu L,Li Q,Lu B,Liang A,Xu GT,Zhu H,Gao Z,Ma J,Xu J,Chen X
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat May 09 00:00:00 EDT 2015
Overexpression of RhoH Permits to Bypass the Pre-TCR Checkpoint.
PloS one
Tamehiro N,Oda H,Shirai M,Suzuki H
14-0441 was used in Flow cytometry/Cell sorting to indicate that an excess amount of RhoH is able to initiate pre-TCR signalling in the absence of pre-TCR complexes.
Mon Apr 25 00:00:00 EDT 2016
Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.
Nature communications
Rouhani SJ,Eccles JD,Riccardi P,Peske JD,Tewalt EF,Cohen JN,Liblau R,Mäkinen T,Engelhard VH
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that when β-galactosidase (β-gal) is expressed in LECs, β-gal-specific CD8 T cells undergo deletion via the PD-1/PD-L1 and LAG-3/MHC-II pathways.
Fri Apr 10 00:00:00 EDT 2015
Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids.
Nature medicine
Khalifeh-Soltani A,McKleroy W,Sakuma S,Cheung YY,Tharp K,Qiu Y,Turner SM,Chawla A,Stahl A,Atabai K
14-0441 was used in Flow cytometry/Cell sorting to suggest a role of Mfge8 in regulating the absorption and storage of dietary fats, and development of obesity.
Sat Feb 01 00:00:00 EST 2014
The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells.
Nature immunology
Xiao N,Eto D,Elly C,Peng G,Crotty S,Liu YC
14-0441 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms that regulate the induction of T(FH) cells, showing that Itch is required.
Tue Jul 01 00:00:00 EDT 2014
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.
The Journal of experimental medicine
Velardi E,Tsai JJ,Holland AM,Wertheimer T,Yu VW,Zakrzewski JL,Tuckett AZ,Singer NV,West ML,Smith OM,Young LF,Kreines FM,Levy ER,Boyd RL,Scadden DT,Dudakov JA,van den Brink MR
14-0441 was used in Flow cytometry/Cell sorting to reveal a novel mechanism underlying improved thymic regeneration upon sex steroid ablation.
Mon Nov 17 00:00:00 EST 2014
Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Cancer research
Ho PC,Meeth KM,Tsui YC,Srivastava B,Bosenberg MW,Kaech SM
14-0441 was used in Flow cytometry/Cell sorting to investigate whether B-Raf(V600E) inhibitors promote tumor regression with the help of host immunity, showing that they rely on signaling by CD40L and IFNγ.
Sun Jun 15 00:00:00 EDT 2014
Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ΔureC::hly vaccine's superior protection against tuberculosis.
The Journal of infectious diseases
Vogelzang A,Perdomo C,Zedler U,Kuhlmann S,Hurwitz R,Gengenbacher M,Kaufmann SH
14-0441 was used in Flow cytometry/Cell sorting to investigate the T-cell population required for recombinant Bacillus Calmette-Guérin δureC::hly vaccine's enhanced protection against tuberculosis.
Mon Dec 15 00:00:00 EST 2014
Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.
PLoS pathogens
Le Saout C,Hasley RB,Imamichi H,Tcheung L,Hu Z,Luckey MA,Park JH,Durum SK,Smith M,Rupert AW,Sneller MC,Lane HC,Catalfamo M
14-0441 was used in Flow cytometry/Cell sorting to define the mechanisms behind immune cell maintenance in HIV infected individuals.
Sat Mar 01 00:00:00 EST 2014
Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.
European journal of immunology
Mayer CT,Ghorbani P,Kühl AA,Stüve P,Hegemann M,Berod L,Gershwin ME,Sparwasser T
14-0441 was used in Flow cytometry/Cell sorting to study the mechanisms underlying why regulatory T cell-depletion fails to cause autoimmunity in adult Depletion of REGulatory T cells mice.
Wed Oct 01 00:00:00 EDT 2014
Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Huang Z,Zhao C,Chen Y,Cowell JA,Wei G,Kultti A,Huang L,Thompson CB,Rosengren S,Frost GI,Shepard HM
14-0441 was used in Immunohistochemistry to indicate that neither rHuPH20 nor its HA catabolites have inflammatory properties in the air pouch model, and can inhibit some inflammation.
Sun Jun 01 00:00:00 EDT 2014
Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions.
Journal of immunology (Baltimore, Md. : 1950)
Duong S,Condotta SA,Rai D,Martin MD,Griffith TS,Badovinac VP
14-0441 was used in Flow cytometry/Cell sorting to study the role of sepsis in shaping the quantity and functionality of infection- or vaccine-induced memory CD8 T cells.
Tue Apr 15 00:00:00 EDT 2014
Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Berkley AM,Fink PJ
14-0441-82 was used in Flow Cytometry to investigate if the maturation state of peripheral T cells impacts the response to bacterial infection due to intrinsic differences in TCR signaling.
Wed Oct 01 00:00:00 EDT 2014
Histone deacetylation critically determines T cell subset radiosensitivity.
Journal of immunology (Baltimore, Md. : 1950)
Pugh JL,Sukhina AS,Seed TM,Manley NR,Sempowski GD,van den Brink MR,Smithey MJ,Nikolich-Žugich J
14-0441 was used in Flow cytometry/Cell sorting to investigate the radiosensitivity of native, effector and central memory T cell subsets.
Fri Aug 01 00:00:00 EDT 2014
B cell-specific loss of Lyn kinase leads to autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Lamagna C,Hu Y,DeFranco AL,Lowell CA
14-0441-82 was used in Flow Cytometry to demonstrate that B cell-intrinsic Lyn-dependent signalling pathways regulate B cell homeostasis and activation.
Sat Feb 01 00:00:00 EST 2014
B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen.
Journal of immunology (Baltimore, Md. : 1950)
Weinstein JS,Bertino SA,Hernandez SG,Poholek AC,Teplitzky TB,Nowyhed HN,Craft J
14-0441 was used in Flow cytometry/Cell sorting to study the role of B cells in the development of Tfh cells and germinal centres.
Tue Apr 01 00:00:00 EDT 2014
Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction.
Tissue engineering. Part A
Ahmed N,Iu J,Brown CE,Taylor DW,Kandel RA
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
CD44 clustering is involved in monocyte differentiation.
Acta biochimica et biophysica Sinica
Zhang G,Zhang H,Liu Y,He Y,Wang W,Du Y,Yang C,Gao F
14-0441 was used in Functional assays to suggest that mechanisms of monocyte differentiation following CD44 activation may include CD44 high expression and clustering, leading to ERK1/2 phosphorylation.
Tue Jul 01 00:00:00 EDT 2014
Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.
Respiratory research
Van de Laar E,Clifford M,Hasenoeder S,Kim BR,Wang D,Lee S,Paterson J,Vu NM,Waddell TK,Keshavjee S,Tsao MS,Ailles L,Moghal N
14-0441 was used in Flow cytometry/Cell sorting to provide the largest description to date of molecular diversity among human large airway basal cells.
Wed Dec 31 00:00:00 EST 2014
Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation.
Neoplasia (New York, N.Y.)
Zhang S,Chung WC,Wu G,Egan SE,Xu K
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2014
FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells.
Oncotarget
Wei HJ,Nickoloff JA,Chen WH,Liu HY,Lo WC,Chang YT,Yang PC,Wu CW,Williams DF,Gelovani JG,Deng WP
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Wed Oct 15 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells.
eLife
Sojka DK,Plougastel-Douglas B,Yang L,Pak-Wittel MA,Artyomov MN,Ivanova Y,Zhong C,Chase JM,Rothman PB,Yu J,Riley JK,Zhu J,Tian Z,Yokoyama WM
14-0441 was used in Flow cytometry/Cell sorting to investigate whether tissue-resident and cells resembling conventional splenic natural killer cells natural killer cells are derived from the same lineage, showing that there are at least four distinct lineages.
Wed Jan 01 00:00:00 EST 2014
Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming.
Nature communications
Harland KL,Day EB,Apte SH,Russ BE,Doherty PC,Turner SJ,Kelso A
14-0441 was used in Flow cytometry/Cell sorting to study whether epigenetic modifications affecting T-cells persist following adoptive transfer of the cells.
Fri Mar 28 00:00:00 EDT 2014
Validation of the effects of TGF-β1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties.
Cancer cell international
Wu TH,Chou YW,Chiu PH,Tang MJ,Hu CW,Yeh ML
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Mar 03 00:00:00 EST 2014
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.
PloS one
May SL,Zhou Q,Lewellen M,Carter CM,Coffey D,Highfill SL,Bucher CM,Matise I,Morse HC,O'Sullivan MG,Schutten M,Johnson C,Bellgrau D,Blazar BR,Modiano JF
14-0441 was used in Flow cytometry/Cell sorting to study how Nfatc2 and Tob1 are non-redundant regulators of lymphocyte homeostasis.
Mon Oct 19 00:00:00 EDT 2015
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
PloS one
Thelemann C,Eren RO,Coutaz M,Brasseit J,Bouzourene H,Rosa M,Duval A,Lavanchy C,Mack V,Mueller C,Reith W,Acha-Orbea H
14-0441 was used in Flow cytometry/Cell sorting to investigate how epithelial MHCII expression is induced and how a deficiency in inducible epithelial MHCII expression alters susceptibility to colitis and the outcome of colon-specific immune responses.
Mon Dec 22 00:00:00 EST 2014
High-resolution analysis with novel cell-surface markers identifies routes to iPS cells.
Nature
O'Malley J,Skylaki S,Iwabuchi KA,Chantzoura E,Ruetz T,Johnsson A,Tomlinson SR,Linnarsson S,Kaji K
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Jul 04 00:00:00 EDT 2013
RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.
Nature
Lukens JR,Vogel P,Johnson GR,Kelliher MA,Iwakura Y,Lamkanfi M,Kanneganti TD
14-0441 was used in Flow cytometry/Cell sorting to investigate how mutations in SHP-1 causes inflammatory disease, showing that RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.
Thu Jun 13 00:00:00 EDT 2013
Hematopoietic progenitor cell lines with myeloid and lymphoid potential.
Nature methods
Redecke V,Wu R,Zhou J,Finkelstein D,Chaturvedi V,High AA,Häcker H
14-0441 was used in Flow cytometry/Cell sorting to develop methods to investigate immune-cell differentiation and function, showing that immortalised hematopoietic progenitor cell lines can be produced, with myeloid and lymphoid potential.
Thu Aug 01 00:00:00 EDT 2013
T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens.
Immunity
Mandl JN,Monteiro JP,Vrisekoop N,Germain RN
14-0441 was used in Flow cytometry/Cell sorting to provide evidence for a connection between thymic recognition events and foreign antigen-driven T cell responses.
Thu Feb 21 00:00:00 EST 2013
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Nature immunology
Gracias DT,Stelekati E,Hope JL,Boesteanu AC,Doering TA,Norton J,Mueller YM,Fraietta JA,Wherry EJ,Turner M,Katsikis PD
14-0441 was used in Flow cytometry/Cell sorting to study the role of miR-155 in the regulation of CD8(+) T cell interferon responses to pathogens in vivo.
Sat Jun 01 00:00:00 EDT 2013
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.
Nature immunology
Kidani Y,Elsaesser H,Hock MB,Vergnes L,Williams KJ,Argus JP,Marbois BN,Komisopoulou E,Wilson EB,Osborne TF,Graeber TG,Reue K,Brooks DG,Bensinger SJ
14-0441 was used in Flow cytometry/Cell sorting to provide insights into the molecular signals that underlie the metabolic reprogramming of CD8(+) T cells during the transition from quiescence to activation.
Wed May 01 00:00:00 EDT 2013
Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells.
Nature immunology
Cohen NR,Brennan PJ,Shay T,Watts GF,Brigl M,Kang J,Brenner MB
14-0441 was used in Flow cytometry/Cell sorting to profile gene expression in invariant natural killer T cells during ontogeny and in peripheral subsets.
Tue Jan 01 00:00:00 EST 2013
Identification of transcriptional regulators in the mouse immune system.
Nature immunology
Jojic V,Shay T,Sylvia K,Zuk O,Sun X,Kang J,Regev A,Koller D,Best AJ,Knell J,Goldrath A,Joic V,Koller D,Shay T,Regev A,Cohen N,Brennan P,Brenner M,Kim F,Rao TN,Wagers A,Heng T,Ericson J,Rothamel K,Ortiz-Lopez A,Mathis D,Benoist C,Bezman NA,Sun JC,Min-Oo G,Kim CC,Lanier LL,Miller J,Brown B,Merad M,Gautier EL,Jakubzick C,Randolph GJ,Monach P,Blair DA,Dustin ML,Shinton SA,Hardy RR,Laidlaw D,Collins J,Gazit R,Rossi DJ,Malhotra N,Sylvia K,Kang J,Kreslavsky T,Fletcher A,Elpek K,Bellemarte-Pelletier A,Malhotra D,Turley S
14-0441 was used in Flow cytometry/Cell sorting to study the transcriptional regulators in the mouse immune system.
Sat Jun 01 00:00:00 EDT 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Feb 01 00:00:00 EST 2013
Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.
Blood
Leonhardt F,Grundmann S,Behe M,Bluhm F,Dumont RA,Braun F,Fani M,Riesner K,Prinz G,Hechinger AK,Gerlach UV,Dierbach H,Penack O,Schmitt-Gräff A,Finke J,Weber WA,Zeiser R
14-0441-82 was used in Flow Cytometry to identify negative regulation of GvHD-related neovascularization by miR-100.
Thu Apr 25 00:00:00 EDT 2013
Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion.
Cancer research
Ferrari-Amorotti G,Fragliasso V,Esteki R,Prudente Z,Soliera AR,Cattelani S,Manzotti G,Grisendi G,Dominici M,Pieraccioli M,Raschellà G,Chiodoni C,Colombo MP,Calabretta B
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Aire deficiency promotes TRP-1-specific immune rejection of melanoma.
Cancer research
Zhu ML,Nagavalli A,Su MA
14-0441 was used in Flow cytometry/Cell sorting to show how Aire deficiency can enhance immune responses against melanoma and offer a logical strategy to enhance immune rejection of melanoma.
Mon Apr 01 00:00:00 EDT 2013
Diacylglycerol kinase ζ limits the generation of natural regulatory T cells.
Science signaling
Schmidt AM,Zou T,Joshi RP,Leichner TM,Pimentel MA,Sommers CL,Kambayashi T
14-0441 was used in Flow cytometry/Cell sorting to identify critical signal events in nT(reg) cell development, showing that diacylglycerol kinase ζ limits the generation of nT(reg) cells.
Tue Nov 26 00:00:00 EST 2013
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast cancer research : BCR
Kaanta AS,Virtanen C,Selfors LM,Brugge JS,Neel BG
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Dec 08 00:00:00 EST 2014
Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.
PLoS pathogens
Hafalla JC,Bauza K,Friesen J,Gonzalez-Aseguinolaza G,Hill AV,Matuschewski K
14-0441 was used in Flow cytometry/Cell sorting to investigate antigenic epitopes in a murine malaria immunisation model.
Wed May 01 00:00:00 EDT 2013
Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sosunov AA,Guilfoyle E,Wu X,McKhann GM,Goldman JE
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Western Blot
Wed Apr 24 00:00:00 EDT 2013
Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sosunov AA,Guilfoyle E,Wu X,McKhann GM,Goldman JE
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Western Blot
Wed Apr 24 00:00:00 EDT 2013
Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection.
Journal of virology
Fulton RB,Weiss KA,Pewe LL,Harty JT,Varga SM
14-0441 was used in Flow cytometry/Cell sorting to investigate the extent to which CD8 T cell response to respiratory syncytial virus is altered with age, showing that age severely diminishes response.
Sun Dec 01 00:00:00 EST 2013
CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells.
Journal of virology
Manzke N,Akhmetzyanova I,Hasenkrug KJ,Trilling M,Zelinskyy G,Dittmer U
14-0441 was used in Flow cytometry/Cell sorting to investigate how both Tregs and CD8(+) T cells influence the cytotoxic activity of conventional CD4(+) T cells during an acute retroviral infection.
Sat Jun 01 00:00:00 EDT 2013
The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability.
Stem cells (Dayton, Ohio)
Szabo AZ,Fong S,Yue L,Zhang K,Strachan LR,Scalapino K,Mancianti ML,Ghadially R
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2013
The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability.
Stem cells (Dayton, Ohio)
Szabo AZ,Fong S,Yue L,Zhang K,Strachan LR,Scalapino K,Mancianti ML,Ghadially R
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2013
The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability.
Stem cells (Dayton, Ohio)
Szabo AZ,Fong S,Yue L,Zhang K,Strachan LR,Scalapino K,Mancianti ML,Ghadially R
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2013
Estrogen and progesterone together expand murine endometrial epithelial progenitor cells.
Stem cells (Dayton, Ohio)
Janzen DM,Cheng D,Schafenacker AM,Paik DY,Goldstein AS,Witte ON,Jaroszewicz A,Pellegrini M,Memarzadeh S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2013
Estrogen and progesterone together expand murine endometrial epithelial progenitor cells.
Stem cells (Dayton, Ohio)
Janzen DM,Cheng D,Schafenacker AM,Paik DY,Goldstein AS,Witte ON,Jaroszewicz A,Pellegrini M,Memarzadeh S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2013
Protective roles of epithelial cells in the survival of adult T-cell leukemia/lymphoma cells.
The American journal of pathology
Miyatake Y,Oliveira AL,Jarboui MA,Ota S,Tomaru U,Teshima T,Hall WW,Kasahara M
14-0441 was used in Flow cytometry/Cell sorting to investigate the possible factors behind the observed high resistance to antileukaemic therapies in patients with ATL.
Wed May 01 00:00:00 EDT 2013
Temporal requirements for B cells in the establishment of CD4 T cell memory.
Journal of immunology (Baltimore, Md. : 1950)
Mollo SB,Zajac AJ,Harrington LE
14-0441 was used in Flow cytometry/Cell sorting to demonstrate the temporally and functionally distinct roles for B cells in regulating CD4 T cell responses.
Sun Dec 15 00:00:00 EST 2013
Peripheral tissue homing receptors enable T cell entry into lymph nodes and affect the anatomical distribution of memory cells.
Journal of immunology (Baltimore, Md. : 1950)
Brinkman CC,Rouhani SJ,Srinivasan N,Engelhard VH
14-0441 was used in Flow cytometry/Cell sorting to characterise the expression of different cell surface markers on T cells present within different regions of lymph nodes.
Sun Sep 01 00:00:00 EDT 2013
CD38 controls the innate immune response against Listeria monocytogenes.
Infection and immunity
Lischke T,Heesch K,Schumacher V,Schneider M,Haag F,Koch-Nolte F,Mittrücker HW
14-0441 was used in Flow cytometry/Cell sorting to evaluate the key enzymes governing the innate immune response.
Fri Nov 01 00:00:00 EDT 2013
T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells.
PloS one
Li G,Yang Q,Zhu Y,Wang HR,Chen X,Zhang X,Lu B
14-0441 was used in Flow cytometry/Cell sorting to investigate the role of T-bet and Eomes in shaping the memory T cell pool.
Tue Oct 10 00:00:00 EDT 2017
Increased invasion and tumorigenicity capacity of CD44+/CD24- breast cancer MCF7 cells in vitro and in nude mice.
Cancer cell international
Yan W,Chen Y,Yao Y,Zhang H,Wang T
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Mon Jun 24 00:00:00 EDT 2013
Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.
PloS one
Torrado E,Fountain JJ,Robinson RT,Martino CA,Pearl JE,Rangel-Moreno J,Tighe M,Dunn R,Cooper AM
14-0441 was used in an ELISpot assay to elucidate the role of B cells for the control of mycobacterial infections.
Thu Nov 14 00:00:00 EST 2013
Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.
PloS one
Torrado E,Fountain JJ,Robinson RT,Martino CA,Pearl JE,Rangel-Moreno J,Tighe M,Dunn R,Cooper AM
14-0441 was used in an ELISpot assay to elucidate the role of B cells for the control of mycobacterial infections.
Thu Nov 14 00:00:00 EST 2013
Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo.
PloS one
Duarte JH,Di Meglio P,Hirota K,Ahlfors H,Stockinger B
14-0441 was used in Flow cytometry/Cell sorting to study how the immuno-modulatory effect of TCDD administration for EAE is not the consequence of de novo Treg generation, but the inhibition of Th17 cell differentiation.
Tue Aug 12 00:00:00 EDT 2014
Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo.
PloS one
Wu S,Ju GQ,Du T,Zhu YJ,Liu GH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue Oct 22 00:00:00 EDT 2013
New perspective on dextran sodium sulfate colitis: antigen-specific T cell development during intestinal inflammation.
PloS one
Morgan ME,Zheng B,Koelink PJ,van de Kant HJ,Haazen LC,van Roest M,Garssen J,Folkerts G,Kraneveld AD
14-0441 was used in Flow cytometry/Cell sorting to investigate the specificity of the immune cell response to colitis.
Wed Mar 05 00:00:00 EST 2014
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development.
Immunity
Kageyama R,Cannons JL,Zhao F,Yusuf I,Lao C,Locci M,Schwartzberg PL,Crotty S
14-0441 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying the defects in humoural immunity present in humans and mice deficient in the adaptor protein, SAP.
Fri Jun 29 00:00:00 EDT 2012
Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks.
Nature immunology
Malhotra D,Fletcher AL,Astarita J,Lukacs-Kornek V,Tayalia P,Gonzalez SF,Elpek KG,Chang SK,Knoblich K,Hemler ME,Brenner MB,Carroll MC,Mooney DJ,Turley SJ
14-0441 was used in Flow cytometry/Cell sorting to compare transcriptional characteristics of mouse lymph node stromal cell subsets.
Sun Apr 01 00:00:00 EDT 2012
TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation.
Nature immunology
Zhang N,Bevan MJ
14-0441 was used in Flow cytometry/Cell sorting to propose that TGF-β signaling controls the self-reactivity of peripheral T cells but that in the absence of TGF-β signals, an added trigger such as lymphopenia is needed to drive overt autoimmune disease.
Sun May 27 00:00:00 EDT 2012
Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Chao C,Silverberg MJ,Martínez-Maza O,Chi M,Abrams DI,Haque R,Zha HD,McGuire M,Xu L,Said J
14-0441 was used in Immunohistochemistry to suggest that EBV infection was associated with expression of several tumor markers that are involved in the NF-κB pathway.
Sat Sep 01 00:00:00 EDT 2012
Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice.
Cancer research
Hurez V,Daniel BJ,Sun L,Liu AJ,Ludwig SM,Kious MJ,Thibodeaux SR,Pandeswara S,Murthy K,Livi CB,Wall S,Brumlik MJ,Shin T,Zhang B,Curiel TJ
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that aged anti-tumor effector T-cell function can be improved by reducing age-related immune dysfunction.
Sun Apr 15 00:00:00 EDT 2012
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.
Proceedings of the National Academy of Sciences of the United States of America
Kim TH,Escudero S,Shivdasani RA
14-0441 was used in Immunohistochemistry to study the function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.
Tue Mar 06 00:00:00 EST 2012
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Do JS,Valujskikh A,Vignali DA,Fairchild RL,Min B
14-0441 was used in Flow cytometry/Cell sorting to reveal a previously undefined MHC II-dependent regulation that tunes CD8 T-cell reactivity.
Tue Jul 31 00:00:00 EDT 2012
Increased protection from vaccinia virus infection in mice genetically prone to lymphoproliferative disorders.
Journal of virology
Seedhom MO,Mathurin KS,Kim SK,Welsh RM
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2012
Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation.
Stem cells (Dayton, Ohio)
Paik DY,Janzen DM,Schafenacker AM,Velasco VS,Shung MS,Cheng D,Huang J,Witte ON,Memarzadeh S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Nov 01 00:00:00 EDT 2012
Peroxisome proliferator-activated receptor γ B cell-specific-deficient mice have an impaired antibody response.
Journal of immunology (Baltimore, Md. : 1950)
Ramon S,Bancos S,Thatcher TH,Murant TI,Moshkani S,Sahler JM,Bottaro A,Sime PJ,Phipps RP
14-0441 was used in Flow cytometry/Cell sorting to study how PPARγ expression in B cells is required for an efficient B cell-mediated immune response by regulating B cell differentiation and Ab production.
Thu Nov 15 00:00:00 EST 2012
NIK prevents the development of hypereosinophilic syndrome-like disease in mice independent of IKKα activation.
Journal of immunology (Baltimore, Md. : 1950)
Häcker H,Chi L,Rehg JE,Redecke V
14-0441 was used in Flow cytometry/Cell sorting to show that NF-κB-inducing kinase activity in non-haematopoietic cells controls Th2 cell development and prevents eosinophil-driven inflammatory disease.
Tue May 01 00:00:00 EDT 2012
CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.
Journal of immunology (Baltimore, Md. : 1950)
Wensveen FM,Unger PP,Kragten NA,Derks IA,ten Brinke A,Arens R,van Lier RA,Eldering E,van Gisbergen KP
14-0441 was used in Flow cytometry/Cell sorting to investigate how BIm-dependent apoptosis is initiated in CD8 T cells.
Tue May 01 00:00:00 EDT 2012
MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection.
Journal of immunology (Baltimore, Md. : 1950)
Zuklys S,Mayer CE,Zhanybekova S,Stefanski HE,Nusspaumer G,Gill J,Barthlott T,Chappaz S,Nitta T,Dooley J,Nogales-Cadenas R,Takahama Y,Finke D,Liston A,Blazar BR,Pascual-Montano A,Holländer GA
14-0441 was used in Flow cytometry/Cell sorting to investigate the cues provided by thymic epithelial cells to produce the differentiation of a diverse T cell repertoire, showing that microRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection.
Mon Oct 15 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
14-0441 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
The high and low molecular weight forms of hyaluronan have distinct effects on CD44 clustering.
The Journal of biological chemistry
Yang C,Cao M,Liu H,He Y,Xu J,Du Y,Liu Y,Wang W,Cui L,Hu J,Gao F
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Fluorescence Resonance Energy Transfer (FRET)
Fri Dec 14 00:00:00 EST 2012
The high and low molecular weight forms of hyaluronan have distinct effects on CD44 clustering.
The Journal of biological chemistry
Yang C,Cao M,Liu H,He Y,Xu J,Du Y,Liu Y,Wang W,Cui L,Hu J,Gao F
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Fluorescence Resonance Energy Transfer (FRET)
Fri Dec 14 00:00:00 EST 2012
Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells.
Frontiers in immunology
Chevrier S,Genton C,Malissen B,Malissen M,Acha-Orbea H
14-0441 was used in Flow cytometry/Cell sorting to determine that CD80 and CD86 costimulators play a key role in the polyclonal B cell activation mediated by Lat(Y136F) CD4(+) T cells.
Thu Aug 23 00:00:00 EDT 2012
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha.
Immunity
Hall JA,Cannons JL,Grainger JR,Dos Santos LM,Hand TW,Naik S,Wohlfert EA,Chou DB,Oldenhove G,Robinson M,Grigg ME,Kastenmayer R,Schwartzberg PL,Belkaid Y
14-0441 was used in Flow cytometry/Cell sorting to investigate the role of retinoic acid in responses to infection, showing that it is essential in the promotion of CD4(+) T cell effector responses.
Fri Mar 25 00:00:00 EDT 2011
Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage.
Blood
Hendricks DW,Fink PJ
14-0441 was used in Flow cytometry/Cell sorting to investigate the relationships between recent thymic emigrants and T-helper type 1 and 2 cells.
Thu Jan 27 00:00:00 EST 2011
T(H)17 cells mediate pulmonary collateral priming.
The Journal of allergy and clinical immunology
Albrecht M,Chen HC,Preston-Hurlburt P,Ranney P,Hoymann HG,Maxeiner J,Staudt V,Taube C,Bottomly HK,Dittrich AM
14-0441 was used in Flow cytometry/Cell sorting to analyze whether Th1-polarized pulmonary inflammation also facilitates priming towards new antigens.
Fri Jul 01 00:00:00 EDT 2011
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.
Leukemia
Quéré R,Andradottir S,Brun AC,Zubarev RA,Karlsson G,Olsson K,Magnusson M,Cammenga J,Karlsson S
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Western Blot
Tue Mar 01 00:00:00 EST 2011
Blockade of CTLA-4 decreases the generation of multifunctional memory CD4+ T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Rudolph M,Hebel K,Miyamura Y,Maverakis E,Brunner-Weinzierl MC
14-0441 was used in Flow cytometry/Cell sorting to investigate the role of CTLA-4 on memory formation of adaptive immune responses using anti-CTLA-4 mAb treatment in mice.
Sun May 15 00:00:00 EDT 2011
Development of autoimmune diabetes in the absence of detectable IL-17A in a CD8-driven virally induced model.
Journal of immunology (Baltimore, Md. : 1950)
Van Belle TL,Esplugues E,Liao J,Juntti T,Flavell RA,von Herrath MG
14-0441 was used in Flow cytometry/Cell sorting to elucidate the role of IL-17 in viral infections and type 1 diabetes.
Thu Sep 15 00:00:00 EDT 2011
Rescue of tumor-infiltrating lymphocytes from activation-induced cell death enhances the antitumor CTL response in CD5-deficient mice.
Journal of immunology (Baltimore, Md. : 1950)
Tabbekh M,Franciszkiewicz K,Haouas H,Lécluse Y,Benihoud K,Raman C,Mami-Chouaib F
14-0441-82 was used in Flow Cytometry to compare the T cell response to the B16F10 melanoma engrafted into CD5-deficient and wild-type C57BL/6 mice.
Fri Jul 01 00:00:00 EDT 2011
T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-γ in the absence of antigen.
Journal of immunology (Baltimore, Md. : 1950)
Bou Ghanem EN,Nelson CC,D'Orazio SE
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that the microenvironment in L. monocytogenes-infected BALB/c mice is sufficient to induce responsive CD8(+) T cells to rapidly secrete IFN-γ.
Tue Feb 01 00:00:00 EST 2011
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950)
Busche A,Schmitz S,Fleige H,Robbins SH,Walzer T,Stewart CA,Förster R,Messerle M,Prinz I
14-0441 was used in Flow cytometry/Cell sorting to determine that antiviral immune responses may induce sustained alterations in natural killer cell populations.
Tue Mar 01 00:00:00 EST 2011
B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus.
Journal of immunology (Baltimore, Md. : 1950)
Salek-Ardakani S,Choi YS,Rafii-El-Idrissi Benhnia M,Flynn R,Arens R,Shoenberger S,Crotty S,Croft M,Salek-Ardakani S
14-0441 was used in Flow cytometry/Cell sorting to determine the effects of B7-1 and B7-2 interactions on follicular Th (T(FH)) cell function in response to vaccinia virus.
Sun May 01 00:00:00 EDT 2011
TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B.
Journal of immunology (Baltimore, Md. : 1950)
Gaddis DE,Michalek SM,Katz J
14-0441 was used in Flow cytometry/Cell sorting to investigate how the stimulation of dendritic cells with recombinant haemagglutinin B affects the activation and differentiation of T cells in mice.
Sun May 15 00:00:00 EDT 2011
Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Weiss KA,Christiaansen AF,Fulton RB,Meyerholz DK,Varga SM
14-0441 was used in Flow cytometry/Cell sorting to evaluate the role of IL-10 in the modulation of the respiratory syncytial virus-specific immune response.
Thu Sep 15 00:00:00 EDT 2011
Critical role for invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells.
Immunology letters
Sillé FC,Martin C,Jayaraman P,Rothchild A,Besra GS,Behar SM,Boes M
14-0441 was used in Flow cytometry/Cell sorting to reveal a role for APCs expressing Ii in thymic development and peripheral terminal maturation of iNKT cells.
Fri Sep 30 00:00:00 EDT 2011
GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state.
PloS one
Nadendla SK,Hazan A,Ward M,Harper LJ,Moutasim K,Bianchi LS,Naase M,Ghali L,Thomas GJ,Prowse DM,Philpott MP,Neill GW
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Sep 30 00:00:00 EDT 2011
GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state.
PloS one
Nadendla SK,Hazan A,Ward M,Harper LJ,Moutasim K,Bianchi LS,Naase M,Ghali L,Thomas GJ,Prowse DM,Philpott MP,Neill GW
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Sep 30 00:00:00 EDT 2011
The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells.
BMC immunology
Sprague L,Muccioli M,Pate M,Meles E,McGinty J,Nandigam H,Venkatesh AK,Gu MY,Mansfield K,Rutowski A,Omosebi O,Courreges MC,Benencia F
14-0441 was used in Flow cytometry/Cell sorting to study the effects of different surfaces and soluble factors on the biology of dendritic cells.
Mon Jun 06 00:00:00 EDT 2011
Plasma cells negatively regulate the follicular helper T cell program.
Nature immunology
Pelletier N,McHeyzer-Williams LJ,Wong KA,Urich E,Fazilleau N,McHeyzer-Williams MG
14-0441 was used in Flow cytometry/Cell sorting to study plasma cells, showing that they negatively regulate the follicular helper T cell program.
Wed Dec 01 00:00:00 EST 2010
Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells.
Blood
Coghill JM,Carlson MJ,Panoskaltsis-Mortari A,West ML,Burgents JE,Blazar BR,Serody JS
14-0441 was used in Flow cytometry/Cell sorting to investigate the role of MHC disparity between donor and recipient, in the attenuated graft-versus-host disease responses of murine T cells lacking CCR7.
Thu Jun 10 00:00:00 EDT 2010
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway.
The Journal of experimental medicine
Hubert S,Rissiek B,Klages K,Huehn J,Sparwasser T,Haag F,Koch-Nolte F,Boyer O,Seman M,Adriouch S
14-0441 was used in Flow cytometry/Cell sorting to demonstrate that NAD(+) influences survival, phenotype, and function of Treg cells.
Mon Nov 22 00:00:00 EST 2010
PTEN loss accelerates KrasG12D-induced pancreatic cancer development.
Cancer research
Hill R,Calvopina JH,Kim C,Wang Y,Dawson DW,Donahue TR,Dry S,Wu H
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2010
Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma.
Cancer research
Klages K,Mayer CT,Lahl K,Loddenkemper C,Teng MW,Ngiow SF,Smyth MJ,Hamann A,Huehn J,Sparwasser T
14-0441 was used in Flow cytometry/Cell sorting to suggest that selective Treg targeting strategies combined with vaccinations against tumor-associated (self) antigens have the potential to evoke efficient antitumor responses without inducing overt autoimmunity.
Fri Oct 15 00:00:00 EDT 2010
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.
Proceedings of the National Academy of Sciences of the United States of America
Jin HT,Anderson AC,Tan WG,West EE,Ha SJ,Araki K,Freeman GJ,Kuchroo VK,Ahmed R
14-0441 was used in Flow cytometry/Cell sorting to define a parameter for determining the severity of CD8 T cell dysfunction and show that targeting PD-1 and Tim-3 is an effective strategy for treating chronic viral infections.
Tue Aug 17 00:00:00 EDT 2010
Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for beta-selection and TCR repertoire formation.
Proceedings of the National Academy of Sciences of the United States of America
Ishikawa E,Miyake Y,Hara H,Saito T,Yamasaki S
14-0441 was used in Flow cytometry/Cell sorting to investigate the mechanism underlying this ligand-independent pre-T-cell receptor (TCR) signalling in vivo, showing that germ-line elimination of electric charge on pre-T-cell receptor impairs autonomous signaling for beta-selection and TCR repertoire formation.
Tue Nov 16 00:00:00 EST 2010
Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites.
PLoS pathogens
Schmidt NW,Butler NS,Badovinac VP,Harty JT
14-0441 was used in Flow cytometry/Cell sorting to identify and track whole-parasite, RAS-vaccine-induced effector and memory CD8 T cell responses.
Thu Jul 15 00:00:00 EDT 2010
Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells.
PLoS pathogens
Wilson DC,Grotenbreg GM,Liu K,Zhao Y,Frickel EM,Gubbels MJ,Ploegh HL,Yap GS
14-0441 was used in Flow cytometry/Cell sorting to identify a novel H-2K(b)-restricted CTL population specific for the Toxoplasma antigen tgd057.
Fri Mar 19 00:00:00 EDT 2010
Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection.
Journal of immunology (Baltimore, Md. : 1950)
McCarl CA,Khalil S,Ma J,Oh-hora M,Yamashita M,Roether J,Kawasaki T,Jairaman A,Sasaki Y,Prakriya M,Feske S
14-0441 was used in Flow cytometry/Cell sorting to reaffirm the critical role of ORAI1 for T cell function, and provide important insights into the in vivo functions of CRAC channels for T cell-mediated immunity.
Mon Nov 15 00:00:00 EST 2010
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Zhu Y,Ju S,Chen E,Dai S,Li C,Morel P,Liu L,Zhang X,Lu B
14-0441 was used in Flow cytometry/Cell sorting to define T-bet and Eomes as critical regulators of T cell-mediated immune responses against tumours.
Wed Sep 15 00:00:00 EDT 2010
Slam haplotypes modulate the response to lipopolysaccharide in vivo through control of NKT cell number and function.
Journal of immunology (Baltimore, Md. : 1950)
Aktan I,Chant A,Borg ZD,Damby DE,Leenstra PC,Lilley GW,Petty J,Suratt BT,Teuscher C,Wakeland EK,Poynter ME,Boyson JE
14-0441 was used in Flow cytometry/Cell sorting to investigate the effect of Slam haplotypes on NKT cells.
Thu Jul 01 00:00:00 EDT 2010
Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection.
Journal of immunology (Baltimore, Md. : 1950)
Findlay EG,Greig R,Stumhofer JS,Hafalla JC,de Souza JB,Saris CJ,Hunter CA,Riley EM,Couper KN
14-0441 was used in Flow cytometry/Cell sorting to demonstrate the essential role of IL-27R signalling in regulating effector T cell function during malaria infection.
Sun Aug 15 00:00:00 EDT 2010
CD44 expression is developmentally regulated in the mouse lens and increases in the lens epithelium after injury.
Differentiation; research in biological diversity
Desai VD,Wang Y,Simirskii VN,Duncan MK
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunofluorescence
Mon Feb 01 00:00:00 EST 2010
CD44 expression is developmentally regulated in the mouse lens and increases in the lens epithelium after injury.
Differentiation; research in biological diversity
Desai VD,Wang Y,Simirskii VN,Duncan MK
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Immunofluorescence
Mon Feb 01 00:00:00 EST 2010
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.
Cancer cell
Read TA,Fogarty MP,Markant SL,McLendon RE,Wei Z,Ellison DW,Febbo PG,Wechsler-Reya RJ
14-0441 was used in Flow cytometry/Cell sorting to identify CD15 as a marker for tumour-propagating cells in a mouse model of medulloblastoma.
Tue Feb 03 00:00:00 EST 2009
Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response.
Gastroenterology
Tang L,Yang J,Liu W,Tang X,Chen J,Zhao D,Wang M,Xu F,Lu Y,Liu B,Sun Q,Zhang L,He F
14-0441 was used in Flow cytometry/Cell sorting to investigate the molecular basis of immune suppression in the liver.
Thu Oct 01 00:00:00 EDT 2009
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation.
Nature immunology
Koch MA,Tucker-Heard G,Perdue NR,Killebrew JR,Urdahl KB,Campbell DJ
14-0441 was used in Flow cytometry/Cell sorting to study how in a subset of CD4(+) T cells, the activities of the transcription factors Foxp3 and T-bet are overlaid.
Mon Jun 01 00:00:00 EDT 2009
Differential requirements of MHC and of DCs for endogenous proliferation of different T-cell subsets in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Do JS,Min B
14-0441 was used in Flow cytometry/Cell sorting to investigate the conditions and requirements of MHC and DCs for endogenous proliferation of different T-cell subsets.
Tue Dec 01 00:00:00 EST 2009
Caspase-2 activation in the absence of PIDDosome formation.
The Journal of cell biology
Manzl C,Krumschnabel G,Bock F,Sohm B,Labi V,Baumgartner F,Logette E,Tschopp J,Villunger A
14-0441 was used in Flow cytometry/Cell sorting to suggest at least one alternative PIDDosome-independent mechanism of caspase-2 activation exists in mammals in response to DNA damage.
Mon Apr 20 00:00:00 EDT 2009
Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway.
PLoS pathogens
Kemball CC,Harkins S,Whitmire JK,Flynn CT,Feuer R,Whitton JL
14-0441 was used in Flow cytometry/Cell sorting to evaluate in vitro and in vivo antigen presentation by coxsackievirus B3, showing that it inhibits antigen presentation in vivo.
Thu Oct 01 00:00:00 EDT 2009
Mice deficient in stem cell antigen-1 (Sca1, Ly-6A/E) develop normal primary and memory CD4+ and CD8+ T-cell responses to virus infection.
European journal of immunology
Whitmire JK,Eam B,Whitton JL
14-0441 was used in Flow cytometry/Cell sorting to evaluate the requirement for Sca1 in the T-cell response to viral infection.
Mon Jun 01 00:00:00 EDT 2009
Critical roles of lysosomal acid lipase in T cell development and function.
The American journal of pathology
Qu P,Du H,Wilkes DS,Yan C
14-0441-82 was used in Flow Cytometry to conclude that the altered development and function of lal(-/-) T cells contributes to disease formation in various organs during LAL deficiency.
Sun Mar 01 00:00:00 EST 2009
Chronic CD70-driven costimulation impairs IgG responses by instructing T cells to inhibit germinal center B cell formation through FasL-Fas interactions.
Journal of immunology (Baltimore, Md. : 1950)
Beishuizen CR,Kragten NA,Boon L,Nolte MA,van Lier RA,van Gisbergen KP
14-0441 was used in Flow cytometry/Cell sorting to investigate the mechanism by which CD70 expression induces T cell-driven disruption of neutralising Ab responses, showing that this occurs by instructing T cells to inhibit germinal center B cell formation.
Sun Nov 15 00:00:00 EST 2009
GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950)
van Olffen RW,Koning N,van Gisbergen KP,Wensveen FM,Hoek RM,Boon L,Hamann J,van Lier RA,Nolte MA
14-0441 was used in Flow cytometry/Cell sorting to study the role of glucocorticoid-induced TNF receptor family-related protein on activated and regulatory T cells.
Mon Jun 15 00:00:00 EDT 2009
ICOS controls effector function but not trafficking receptor expression of kidney-infiltrating effector T cells in murine lupus.
Journal of immunology (Baltimore, Md. : 1950)
Odegard JM,DiPlacido LD,Greenwald L,Kashgarian M,Kono DH,Dong C,Flavell RA,Craft J
14-0441 was used in Flow cytometry/Cell sorting to show that ICOS is strictly required for local inflammatory functions of autoreactive CD4 T cells in the renal pathology of murine lupus.
Wed Apr 01 00:00:00 EDT 2009
Two host factors regulate persistence of H7-specific T cells injected in tumor-bearing mice.
PloS one
Meunier MC,Baron C,Perreault C
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Fri Feb 13 00:00:00 EST 2009
Effects of Culturing on the Stability of the Putative Murine Adipose Derived Stem Cells Markers.
The open stem cell journal
Maddox JR,Liao X,Li F,Niyibizi C
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2009
Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines.
Blood
Ahonen CL,Wasiuk A,Fuse S,Turk MJ,Ernstoff MS,Suriawinata AA,Gorham JD,Kedl RM,Usherwood EJ,Noelle RJ
14-0441 was used in Flow cytometry/Cell sorting to report the therapeutic effects of combinatorial use of CD40 and TLR agonists as a cancer vaccine.
Sat Mar 15 00:00:00 EDT 2008
ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America
Reiley WW,Calayag MD,Wittmer ST,Huntington JL,Pearl JE,Fountain JJ,Martino CA,Roberts AD,Cooper AM,Winslow GM,Woodland DL
14-0441 was used in Flow cytometry/Cell sorting to directly show that T cell priming to ESAT-6 occurs only after 10 days of aerosol Mycobacterium tuberculosis infection.
Tue Aug 05 00:00:00 EDT 2008
Enumeration and functional evaluation of virus-specific CD4+ and CD8+ T cells in lymphoid and peripheral sites of coxsackievirus B3 infection.
Journal of virology
Kemball CC,Harkins S,Whitton JL
14-0441 was used in Flow cytometry/Cell sorting to evaluate CVB3 epitope-specific CD8(+) and CD4(+) T-cell responses in the spleen, heart and pancreas of mice in vivo.
Thu May 01 00:00:00 EDT 2008
Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease.
The Journal of experimental medicine
Sather BD,Treuting P,Perdue N,Miazgowicz M,Fontenot JD,Rudensky AY,Campbell DJ
14-0441 was used in Flow cytometry/Cell sorting to investigate the factors which impact regulatory T cell homing receptor expression, tissue distribution and peripheral tolerance maintenance.
Mon Jun 11 00:00:00 EDT 2007
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency.
Proceedings of the National Academy of Sciences of the United States of America
Porubsky S,Speak AO,Luckow B,Cerundolo V,Platt FM,Gröne HJ
14-0441 was used in Flow cytometry/Cell sorting to investigate the role of iGb3 in iNKT cell selection.
Tue Apr 03 00:00:00 EDT 2007
Isolation of murine hair-inducing cells using the cell surface marker prominin-1/CD133.
The Journal of investigative dermatology
Ito Y,Hamazaki TS,Ohnuma K,Tamaki K,Asashima M,Okochi H
14-0441 was used in Flow cytometry/Cell sorting to propose that the CD133 is a novel surface marker useful for collecting DP cells in the anagen stage.
Tue May 01 00:00:00 EDT 2007
Amelioration of coxsackievirus B3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1.
The American journal of pathology
Crocker SJ,Frausto RF,Whitmire JK,Benning N,Milner R,Whitton JL
14-0441 was used in Flow cytometry/Cell sorting to show that TIMP-1 expression is induced in the myocardium by CVB3 infection.
Sat Dec 01 00:00:00 EST 2007
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
Published figure using CD44 monoclonal antibody (Product # 14-0441-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2007