Leinco Technologies

CD54 Monoclonal Antibody (YN1/1.7.4), Functional Grade, In Vivo PLATINUM™

Name: CD54 Monoclonal Antibody (YN1\/1.7.4), Functional Grade, In Vivo PLATINUM\u2122
Brand: Leinco Technologies
SKU: C6391-1MG

查看其他114个ICAM-1 (CD54)抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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CD54 Antibody (C6391-1MG) in WB

Western Blot analysis of ICAM-1 (CD54) in A-20 whole cell lysate and reduced recombinant mouse CD54 protein using CD54 Monoclonal Antibody (Product # C6391-1MG).

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Immunogen image

Immunogen Image CD54 Monoclonal Antibody (YN1/1.7.4), Functional Grade, In Vivo PLATINUM™

产品信息

C6391-1MG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化（冰冻） (IHC (F))

Assay-dependent

流式细胞分析 (Flow)

Assay-dependent

免疫沉淀 (IP)

Assay-dependent

功能检测 (Functional)

Assay-dependent

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

YN1/1.7.4

抗原

Mouse NS-1 cells

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偶联物

Functional Grade Functional Grade Functional Grade

形式

Liquid

浓度

≥5.0 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.2-7.4

内含物

no preservative

保存条件

4°C short term, -80°C long term

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Specificity: Clone YN1/1.7.4 recognizes an epitope on mouse CD54.

Endotoxin Level: <0.5 EU/mg as determined by the LAL method. Purity: >95% by SDS Page; ≥98% monomer by analytical SEC.

Product Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco Purified Functional PLATINUM™ antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.

Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80 C. Avoid Repeated Freeze Thaw Cycles.

This antibody has been tested in the following applications: Western Blotting, Immunoprecipitation, Immunohistochemistry-Fresh Frozen, Functional Assay, Flow Cytometry, CyTOF® CODEX®.

靶标信息

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD54; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; MALA-2; MALA2; MyD10; sCD54; soluble CD54; Surface antigen of activated B cells

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基因别名: CD54; Icam-1; Icam1; Ly-47; MALA-2

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UniProt ID: (Mouse) P13597

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Entrez Gene ID: (Mouse) 15894

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功能

integrin binding protein complex binding

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