NeoBiotechnologies

CD6 (Negative Marker of T-regulatory Cells) Recombinant Rabbit Monoclonal Antibody (C6/7022R)

CD6 (Negative Marker of T-regulatory Cells) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD6 (Negative Marker of T-regulatory Cells) Antibody (923-RBM7-P0) in IHC (P)

IHC analysis of Formalin-fixed, paraffin-embedded human spleen. Staining using C6/7022R at 2 µg/mL in PBS for 30 min RT. Inset: PBS instead of primary antibody; secondary only negative control.

CD6 (Negative Marker of T-regulatory Cells) Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

923-RBM7-P0

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

2 µg/mL

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

C6/7022R

抗原

Human recombinant full-length CD6 protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C, do not freeze

运输条件

Wet ice

靶标信息

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。