Invitrogen

CD64 Monoclonal Antibody (10.1)

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CD64 Antibody (MA5-16435) in Flow

Flow cytometric analysis of peripheral blood monocytes with Mouse anti Human CD64

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产品信息

MA5-16435

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

1:50-1:100

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其他PubMed (Misc)

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产品规格

种属反应

Human, Non-human primate

已发表种属

Human, Non-human primate

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

10.1

抗原

Human monocytes

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2537950

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

靶标信息

CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System.

Journal of immunology (Baltimore, Md. : 1950)

Waschbisch A,Schröder S,Schraudner D,Sammet L,Weksler B,Melms A,Pfeifenbring S,Stadelmann C,Schwab S,Linker RA

MA516435 was used in flow cytometry to analyze the frequency and phenotype of monocyte subpopulations in peripheral blood, cerebrospinal fluid, and brain biopsy material derived from multiple sclerosis patients

Mon Feb 15 00:00:00 EST 2016

Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age.

Human immunology

Garbe K,Bratke K,Wagner S,Virchow JC,Lommatzsch M

MA5-16435 was used in flow cytometry to examine the effects of age and gender on TLR9 expression on human DCs.

Tue May 01 00:00:00 EDT 2012

Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.

The Journal of experimental medicine

Willcocks LC,Lyons PA,Clatworthy MR,Robinson JI,Yang W,Newland SA,Plagnol V,McGovern NN,Condliffe AM,Chilvers ER,Adu D,Jolly EC,Watts R,Lau YL,Morgan AW,Nash G,Smith KG

MA5-16435 was used in flow cytometry to examine how FCGR3B copy number affects immune responses

Mon Jul 07 00:00:00 EDT 2008

Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.

Blood

Hirano N,Butler MO,Xia Z,Ansén S,von Bergwelt-Baildon MS,Neuberg D,Freeman GJ,Nadler LM

MA5-16435 was used in flow cytometry to examine the consequences of CD83 ligand engagement on antigen-specific CD8+ T cells

Wed Feb 15 00:00:00 EST 2006

Flow cytometry identification and characterization of mononuclear cell subsets in the neotropical primate Saimiri sciureus (squirrel monkey).

Journal of immunological methods

Contamin H,Loizon S,Bourreau E,Michel JC,Garraud O,Mercereau-Puijalon O,Behr C

MA5-16435 was used in flow cytometry to discuss available reagents for studying the neotropical primate squirrel monkey.

Tue Feb 01 00:00:00 EST 2005

Prognostic significance of CD56 antigen expression in acute myeloid leukemia.

Haematologica

Di Bona E,Sartori R,Zambello R,Guercini N,Madeo D,Rodeghiero F

MA5-16435 was used in flow cytometry to examine CD56 expression in a cohort of acute myeloid leukemia patients in to assess its frequency and prognostic relevance.

Fri Mar 01 00:00:00 EST 2002

生物信息学

蛋白别名: CD64; CD64 antigen; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRIa; FcgRI; FcRI; FLJ18345; High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; RP11-196G18.2

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基因别名: CD64; CD64A; FCG1; FCGR1; FCGR1A; FCRI; IGFR1

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UniProt ID: (Human) P12314

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Entrez Gene ID: (Human) 2209

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功能

receptor signaling protein activity protein binding IgG binding immunoglobulin receptor superfamily

参与通路

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent receptor-mediated endocytosis phagocytosis, engulfment immune response signal transduction Fc-gamma receptor signaling pathway involved in phagocytosis regulation of immune response interferon-gamma-mediated signaling pathway