Proteintech

CD72 Monoclonal Antibody (2C1C6), CoraLite® 594

CD72 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD72 Antibody (CL59467424100UL) in IHC (P)

Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite 594-conjugated CD72 antibody (Product # CL59467424100UL), Clone: 2C1C6 ) at dilution of 1:100.

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产品信息

CL59467424100UL

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:100

免疫细胞化学 (ICC/IF)

1:50-1:500

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

2C1C6

偶联物

CoraLite® 594 CoraLite® 594 CoraLite® 594

激发/发射光谱

593/614 nm

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

内含物

0.05% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles, store in dark

运输条件

Wet ice

靶标信息

CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。