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产品信息
MA5-28568
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
C33
抗原
C91/PL (human HTLV-1+ T cell line)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4° C, do not freeze
运输条件
Wet ice
RRID
AB_2745527
产品详细信息
This antibody recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
靶标信息
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C33 antigen; CD82; CD82 antigen; IA4; Inducible membrane protein R2; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27
基因别名: 4F9; C33; CD82; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27
UniProt ID: (Human) P27701
Entrez Gene ID: (Human) 3732
