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CD8b Chimeric Antibody (MA5-47996) in Flow
Flow Cytometry analysis of CD8b in Mouse lymphocytes using CD8b Chimeric Monoclonal Antibody (Product # MA5-47996). Cells were stained with CD44 Chimeric Monoclonal Antibody (Product # MA5-48017) (isotype control; panel A) or CD8b Chimeric Monoclonal Antibody (panel B) at a concentration of 1 µg/mL for 30 mins at RT. After washing, the bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody and cells analyzed on a flow-cytometer.
产品信息
MA5-47996
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
YTS 156.7.7
抗原
Mouse CD8 (lyt-3).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3074439
产品详细信息
Specificity: The antibody recognises the B epitope of the mouse Lyt-3 (CD8) antigen. Has been used in CD8 subset depletion in vivo and flow cytometry studies.
靶标信息
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD8; CD8alpha; CD8b; CD8beta; Leu-2; Lymphocyte antigen 3; MAL; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3
基因别名: Cd8b; Cd8b1; Ly-3; Ly-C; Lyt-3; Lyt3
UniProt ID: (Mouse) P10300
Entrez Gene ID: (Mouse) 12526
