Invitrogen

CDH17 Monoclonal Antibody (05)

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他37个CDH17抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

CDH17 Antibody in Immunocytochemistry (ICC/IF)

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CDH17 Antibody (MA5-29135) in ICC/IF

Immunofluorescence analysis of Cadherin-17 was performed using 70% confluent log phase Caco-2 and A-431 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with CDH17 Monoclonal Antibody (Product # MA5-29135) at 1:100 in 0.1% BSA, incubated at 4-degree Celsius overnight and then labeled with Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Produc... View More

CDH17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CDH17 Antibody — Antibody specificity was demonstrated by the detection of differential basal expression of the target across cell models owing to their inherent genetic constitution. Immunofluorescence analysis using Anti-CDH17 Monoclonal Antibody (5) (Product # MA5-29135), shows in Plasma membrane localization in Caco-2 cells as compared to A-431 cells which is reported to be low to negative for CDH17 expression. {RE}

产品信息

MA5-29135

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

抗原

Recombinant Human Cadherin-17/LI-cadherin/CDH17 protein (Met1-Met787)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2785058

产品详细信息

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human Cadherin-17/LI-cadherin/CDH17.

靶标信息

CDH17 gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; Cadherin-17; FLJ26931; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT-1; LI cadherin; LI-cadherin; Liver-intestine cadherin; MGC138218; MGC142024

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基因别名: CDH16; CDH17; HPT-1; HPT1

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UniProt ID: (Human) Q12864

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Entrez Gene ID: (Human) 1015

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功能

integrin binding transporter activity proton-dependent oligopeptide secondary active transmembrane transporter activity calcium ion binding cadherin

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