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产品信息
PA5-84929
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Anitgen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792078
产品详细信息
Immunogen sequence: MNKFLTYFPG RRISAEDGLK HEYFRETPLP IDPSMFPTWP AKSEQQRVKR GTSPRPPEGG LGYSQLGDDD LKETGFHL
靶标信息
The PITSLRE beta1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxyterminal domains of PITSLRE beta1, but not by other mutants lacking Histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated alpha, beta or gamma (i.e., PITSLRE A gene, alpha; PITSLRE B gene, beta and PITSLRE C gene, gamma). Some of the isoforms such as PITSLRE alpha1 (T cells) and PITSLRE beta1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously.
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生物信息学
蛋白别名: CDK11 p110; CDK11 p46; CDK11 p58; cell division cycle 2-like 2 (PITSLRE proteins); Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cyclin-dependent kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE B; PITSLRE protein kinase beta; PITSLRE serine/threonine-protein kinase CDC2L2
基因别名: CDC2L2; CDC2L3; CDK11-p110; CDK11-p46; CDK11-p58; CDK11A; p58GTA; PITSLRE; PITSLREB
UniProt ID: (Human) Q9UQ88
Entrez Gene ID: (Human) 728642
