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CDX2 Antibody (CF500251) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDX2 (RC204883, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CDX2. Positive lysates LY420044 (100 µg) and LC420044 (20 µg) can be purchased separately from OriGene.
产品信息
CF500251
产品规格
种属反应
Dog,
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI1A3
抗原
Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
偶联物
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
基因别名: CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626
Entrez Gene ID: (Dog) 486028, (Human) 1045
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
trophectodermal cell differentiation
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
endosome to lysosome transport
organ morphogenesis
anterior/posterior axis specification
regulation of somitogenesis
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
labyrinthine layer development
