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CEACAM3 Antibody (PA5-96177) in WB
Western blot analysis of CEACAM3 in A549 cells. Samples were incubated with CEACAM3 Polyclonal antibody (Product # PA5-96177) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-96177
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human CD66d/CEACAM3 (NP_0018062)
偶联物
形式
Liquid
浓度
1.71 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807979
产品详细信息
Immunogen sequence: MGPPSASPHR ECIPWQGLLL TASLLNFWNP PTTAKLTIES MPLSVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNSLIV GYVIGTQQAT PGAAYSGRET IYTNASLLIQ NVTQNDIGFY TLQVIKSDLV NEEAT; Positive Samples: A-549, Mouse spleen; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Carcinoembryonic antigen CGM1; carcinoembryonic antigen gene family member 1; Carcinoembryonic antigen-related cell adhesion molecule 3; CD66d; CD66d antigen; nonspecific cross-reacting antigen; pregnancy-specific glycoprotein 24
基因别名: CD66D; CEA; cea12; CEACAM3; CGM1; EG384557; Psg24; W264; W282
UniProt ID: (Human) P40198
Entrez Gene ID: (Human) 1084, (Mouse) 384557
