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Percent identity with other species by BLAST analysis: Human, Bovine, Dog, Panda (100%) Elephant, Rabbit (95%) Gibbon, Rat (90%) Mouse (85%).
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adhesion G protein-coupled receptor C2; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; Epidermal growth factor-like protein 2; Flamingo homolog 3; FLJ34118; FLJ42737; FLJ45143; FLJ45845; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; Multiple epidermal growth factor-like domains protein 3
基因别名: ADGRC2; CDHF10; CELSR2; EGFL2; Flamingo1; KIAA0279; MEGF3
UniProt ID: (Human) Q9HCU4
Entrez Gene ID: (Human) 1952, (Bovine) 538194, (Dog) 479916
分子生物学功能:
cadherin