Search Thermo Fisher Scientific
Peptide sequence: CDLEVEGFRA TMAQRLVRVL QICAGHVPGV SALNLLSLLR SSEGPSLEDL
Sequence homology: Cow: 79%; Dog: 79%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 93%
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bK250D10.2; CENP-M; Centromere protein M; Interphase centromere complex protein 39; MGC861; Proliferation-associated nuclear element protein 1
基因别名: C22orf18; CENP-M; CENPM; ICEN39; PANE1
UniProt ID: (Human) Q9NSP4
Entrez Gene ID: (Human) 79019