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This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: centrosomal protein 120kDa; Centrosomal protein of 120 kDa; Cep120; coiled-coil domain containing 100; Coiled-coil domain-containing protein 100
基因别名: A230075C01; AU016693; CCDC100; CEP120; RGD1565619; SRTD13
UniProt ID: (Human) Q8N960, (Mouse) Q7TSG1
Entrez Gene ID: (Human) 153241, (Rat) 307302, (Mouse) 225523