Search Thermo Fisher Scientific
图: 1 / 6
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Carboxyesterase ES-1; carboxyesterase ES-3; carboxylesterase 1; carboxylesterase 1-like; Carboxylesterase 1C; carboxylesterase 1E; E1; egasyn; ES-HTEL; ES-THET; esterase 1; Esterase 2 member of carboxylesterase-cluster 1; esterase 2, member of carboxylesterase-cluster 1; esterase 22; Esterase-2; Liver carboxylesterase 1; liver carboxylesterase 3; MGC117365; Neutral retinyl ester hydrolase; NREH; pI 5.5 esterase; REH; Retinyl ester hydrolase; triacylglycero
基因别名: Ces1; Ces1c; Es1; Es2; Es22
UniProt ID: (Rat) P10959
Entrez Gene ID: (Rat) 679817, (Rat) 24346, (Rat) 29225