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This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; MICOS complex subunit MIC19; mitochondrial inner membrane organizing system 3; protein phosphatase 1, regulatory subunit 22
基因别名: CHCHD3; MIC19; MINOS3; PPP1R22
UniProt ID: (Human) Q9NX63
Entrez Gene ID: (Human) 54927