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产品信息
H00027243-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHMP2A (AAH02502, 1 a.a. approximately 222 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS NLPSTGGSLS VAAGGKKAEA AASALADADA DLEERLKNLR RD
靶标信息
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 2a; CHMP2a; chromatin modifying protein 2A; Chromatin-modifying protein 2a; putative breast adenocarcinoma marker (32kD); Putative breast adenocarcinoma marker BC-2; Vacuolar protein sorting-associated protein 2-1; VPS2 homolog A; Vps2-1
基因别名: BC-2; BC2; CHMP2; CHMP2A; VPS2; VPS2A
UniProt ID: (Human) O43633
Entrez Gene ID: (Human) 27243
cell separation after cytokinesis
autophagy
nucleus organization
mitotic metaphase plate congression
membrane invagination
exit from mitosis
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
nuclear envelope reassembly
multivesicular body assembly
viral budding via host ESCRT complex
establishment of protein localization
regulation of viral process
protein polymerization
protein homooligomerization
protein heterooligomerization
negative regulation of cell death
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
positive regulation of exosomal secretion
negative regulation of centriole elongation
ESCRT III complex disassembly
