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产品信息
CF810226
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI4B9
抗原
Full length human recombinant protein of human CHP produced in HEK293T cell.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcineurin B homolog; Calcineurin B homologous protein 1; Calcineurin B-like protein; calcineurin homologous protein; calcineurin-like EF hand protein 1; calcineurin-like EF-hand protein 1; calcium binding protein P22; Calcium-binding protein CHP; Calcium-binding protein p22; EF-hand Ca2+-binding protein p22; EF-hand calcium-binding domain-containing protein p22; p24; Sid 470; SLC9A1 binding protein
基因别名: 1500003O03Rik; AA960066; AI046351; Cahp; CHP; CHP1; p22; p24; Sid470; Sid470p; SLC9A1BP; vac; Wrch2
UniProt ID: (Human) Q99653, (Rat) P61023, (Mouse) P61022
Entrez Gene ID: (Human) 11261, (Rat) 64152, (Mouse) 56398
microtubule bundle formation
negative regulation of protein phosphorylation
negative regulation of protein kinase activity
protein export from nucleus
negative regulation of phosphatase activity
calcium ion regulated exocytosis
calcium-mediated signaling
membrane docking
cytoplasmic microtubule organization
negative regulation of protein ubiquitination
negative regulation of protein autophosphorylation
negative regulation of NF-kappaB transcription factor activity
positive regulation of sodium:proton antiporter activity
negative regulation of protein import into nucleus
transcytosis
protein stabilization
positive regulation of protein transport
protein oligomerization
regulation of intracellular pH
positive regulation of protein glycosylation
membrane organization
membrane fusion
negative regulation of calcineurin-NFAT signaling cascade
cellular response to acidic pH
positive regulation of protein targeting to membrane
regulation of neuron death
transport
protein transport
potassium ion transport
small GTPase mediated signal transduction
hyaluronan catabolic process
