Abnova

CIDEA Polyclonal Antibody, MaxPab™

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CIDEA Antibody (H00001149-D01P) in WB

Western Blot analysis of CIDEA expression in transfected 293T cell line (H00001149-T01) by CIDEA MaxPab polyclonal antibody.

Lane 1: CIDEA transfected lysate(28.30 KDa).
Lane 2: Non-transfected lysate.

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产品信息

H00001149-D01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

CIDEA (NP_938031.1, 1 a.a. approximately 253 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MRGDRASGGP GNHNGSWARE GPRLGPSWKR GLWSPRGGPN RPAEPSRPLT FMGSQTKRVL FTPLMHPARP FRVSNHDRSS RRGVMASSLQ ELISKTLDAL VIATGLVTLV LEEDGTVVDT EEFFQTLGDN THFMILEKGQ KWMPGSQHVP TCSPPKRSGI ARVTFDLYRL NPKDFIGCLN VKATMYEMYS VSYDIRCTGL KGLLRSLLRF LSYSAQVTGQ FLIYLGTYML RVLDDKEERP SLRSQAKGRF TCG

靶标信息

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。