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产品信息
12287-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CIDEC Fusion Protein Ag2913 (1-238 aa encoded by BC016851)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
12287-1-AP recognizing CIDEC (calculated 28 kDa) as a 30 kDa and 45-50 kDa due to its posttranslational modification.
Immunogen sequence: MEYAMKSLS LLYPKSLSRH VSVRTSVVTQ QLLSEPSPKA PRARPCRVST ADRSVRKGIM AYSLEDLLLK VRDTLMLADK PFFLVLEEDG TTVETEEYFQ ALAGDTVFMV LQKGQKWQPP SEQGTRHPLS LSHKPAKKID VARVTFDLYK LNPQDFIGCL NVKATFYDTY SLSYDLHCCG AKRIMKEAFR WALFSMQATG HVLLGTSCYL QQLLDATEEG QPPKGKASSL IPTCLKILQ (1-238 aa encoded by BC016851 )
靶标信息
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cell death activator CIDE-3; cell death-inducing DFFA-like effector c; Cell death-inducing DFFA-like effector protein C; CID; cide 3; fat specific protein 27; Fat-specific protein FSP27 homolog; Lipid transferase CIDEC
基因别名: CIDE-3; CIDE3; CIDEC; FPLD5; FSP27
UniProt ID: (Human) Q96AQ7
Entrez Gene ID: (Human) 63924
