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CIDEC Antibody (PA5-30793) in ICC/IF
CIDEC Polyclonal Antibody detects CIDEC protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CIDEC protein stained by CIDEC Polyclonal Antibody (Product # PA5-30793) diluted at 1:500. Blue: Hoechst 33343 staining.
产品信息
PA5-30793
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 53 and 238 of Human CIDEC
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548267
产品详细信息
Recommended positive controls: HeLa, HepG2.
Predicted reactivity: Pig (81%), Sheep (84%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cell death activator CIDE-3; cell death-inducing DFFA-like effector c; Cell death-inducing DFFA-like effector protein C; CID; cide 3; fat specific protein 27; Fat-specific protein FSP27 homolog; Lipid transferase CIDEC
基因别名: CIDE-3; CIDE3; CIDEC; FPLD5; FSP27
UniProt ID: (Human) Q96AQ7
Entrez Gene ID: (Human) 63924
