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产品信息
A304-360A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 to 50 of human Casein Kinase I Isoform gamma-1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine
靶标信息
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha' beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
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生物信息学
蛋白别名: casein kinase 1, gamma 1; Casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK I gamma1; CK-I gamma1; CK1G1; CKI gamma 1; CKI gamma-1; CKI gamma1; CKI- gamma1; CKI-gamma 1; CKI-gamma-1; KC1G1
基因别名: 9130020E21Rik; CK1gamma1; CSNK1G1
UniProt ID: (Human) Q9HCP0, (Mouse) Q8BTH8
Entrez Gene ID: (Human) 53944, (Mouse) 214897
magnesium ion binding
glycoprotein binding
protein serine/threonine kinase activity
protein binding
ATP binding
peptide binding
phosphoprotein binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
