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Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MWQVTAFLDH NIVTAQTTWK GLWMSCVVQS TGHMQCKVYD SVLALSTEVQ AAR
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Claudin-5; TMDVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome
基因别名: AWAL; BEC1; CLDN5; CPETRL1; TMVCF
UniProt ID: (Human) O00501
Entrez Gene ID: (Human) 7122