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CLEC5A Antibody (PA5-47307) in IHC (P)
Immunohistochemical analysis of CLEC5A in formalin fixed paraffin-embedded sections of human rheumatoid arthritis joint. Samples were incubated in CLEC5A polyclonal antibody (Product # PA5-47307) using a dilution of 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to plasma... View More
产品信息
PA5-47307
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human MDL-1/CLEC5A Tyr26-Lys188
偶联物
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2576926
产品详细信息
In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant mouse MDL-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin domain family 5, member A; C-type lectin superfamily member 5; MDL-1; Myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1
基因别名: CLEC5A; CLECSF5; MDL-1; MDL1
UniProt ID: (Human) Q9NY25
Entrez Gene ID: (Human) 23601
