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Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: CNGA1.
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cGMP-gated cation channel alpha-1; cng channel; CNG channel alpha-1; CNG-1; CNG1; cyclic nucleotide gated channel, cGMP gated; Cyclic nucleotide-gated cation channel 1; Cyclic nucleotide-gated channel alpha-1; Cyclic nucleotide-gated channel, photoreceptor; Rod photoreceptor cGMP-gated channel subunit alpha
基因别名: Cncg; Cncg1; Cnga1; HCN
UniProt ID: (Mouse) P29974, (Rat) Q62927
Entrez Gene ID: (Mouse) 12788, (Rat) 85259
分子生物学功能:
ligand-gated ion channel