Proteintech

CNRIP1 Polyclonal Antibody

CNRIP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CNRIP1 Antibody (16827-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse kidney tissue slide using 16827-1-AP ( CNRIP1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

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产品信息

16827-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:50-1:500

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

CNRIP1 Fusion Protein Ag10428 (1-164 aa encoded by BC011535)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.23 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MGDLPGLVR LSIALRIQPN DGPVFYKVDG QRFGQNRTIK LLTGSSYKVE VKIKPSTLQV ENISIGGVLV PLELKSKEPD GDRVVYTGTY DTEGVTPTKS GERQPIQITM PFTDIGTFET VWQVKFYNYH KRDHCQWGSP FSVIEYECKP NETRSLMWVN KESFL (1-164 aa encoded by BC011535)

靶标信息

The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS), while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Disrupting cannabinoid receptor interacting protein 1 rescues cognitive flexibility in long-term estrogen-deprived female mice.

Brain research bulletin

Yang F,Zhao YJ,Chen SJ,Li YR,Yang PY,Qi JY,Wang XS,Wang M,Li XB,Feng B,Wu YM,Liu SB,Zhang K

Fri Apr 01 00:00:00 EDT 2022

Disrupting cannabinoid receptor interacting protein 1 rescues cognitive flexibility in long-term estrogen-deprived female mice.

Brain research bulletin

Yang F,Zhao YJ,Chen SJ,Li YR,Yang PY,Qi JY,Wang XS,Wang M,Li XB,Feng B,Wu YM,Liu SB,Zhang K

Fri Apr 01 00:00:00 EDT 2022

DNA Methylation of Cannabinoid Receptor Interacting Protein 1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin-Dependent Pyruvate Kinase M2 Ubiquitination.

Hepatology (Baltimore, Md.)

Chen D,Wu H,Feng X,Chen Y,Lv Z,Kota VG,Chen J,Wu W,Lu Y,Liu H,Zhang Y,Zheng S,Wu J

Sat May 01 00:00:00 EDT 2021

DNA Methylation of Cannabinoid Receptor Interacting Protein 1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin-Dependent Pyruvate Kinase M2 Ubiquitination.

Hepatology (Baltimore, Md.)

Chen D,Wu H,Feng X,Chen Y,Lv Z,Kota VG,Chen J,Wu W,Lu Y,Liu H,Zhang Y,Zheng S,Wu J

Sat May 01 00:00:00 EDT 2021

DNA Methylation of Cannabinoid Receptor Interacting Protein 1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin-Dependent Pyruvate Kinase M2 Ubiquitination.

Hepatology (Baltimore, Md.)

Chen D,Wu H,Feng X,Chen Y,Lv Z,Kota VG,Chen J,Wu W,Lu Y,Liu H,Zhang Y,Zheng S,Wu J

Sat May 01 00:00:00 EDT 2021

DNA Methylation of Cannabinoid Receptor Interacting Protein 1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin-Dependent Pyruvate Kinase M2 Ubiquitination.

Hepatology (Baltimore, Md.)

Chen D,Wu H,Feng X,Chen Y,Lv Z,Kota VG,Chen J,Wu W,Lu Y,Liu H,Zhang Y,Zheng S,Wu J

Sat May 01 00:00:00 EDT 2021

生物信息学

蛋白别名: cannabinoid receptor CB1-interacting protein 1; CB1 cannabinoid receptor interacting; CB1 cannabinoid receptor-interacting protein 1; CRIP-1

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基因别名: 1500041B16Rik; 3110054C06Rik; 5330437A18Rik; AI854501; C2orf32; CNRIP1; CRIP1; Crip1a; RGD1308373

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UniProt ID: (Human) Q96F85, (Mouse) Q5M8N0, (Rat) Q5M7A7

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Entrez Gene ID: (Human) 25927, (Mouse) 380686, (Rat) 364208

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功能

molecular_function

参与通路

biological_process