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Invitrogen
COL17A1 Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-60461
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640013
产品详细信息
Immunogen sequence: DGTEVTERIV TETVTTRLTS LPPKGGTSNG YAKTASLGGG SRLEKQSLTH GSSGYINSTG STRGHASTSS YRRAHSPAST LPNSPGSTFE RKTHVTR
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
靶标信息
COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 180 kDa bullous pemphigoid antigen 2; alpha 1 type XVII collagen; bA16H23.2 (collagen, type XVII, alpha 1 (BP180)); Bullous pemphigoid antigen 2; bullous pemphigoid antigen 2 (180kD); Collagen alpha-1(XVII) chain; collagen XVII, alpha-1 polypeptide; collagen, type XVII, alpha 1; type XVII collagen alpha-1
基因别名: BA16H23.2; BP180; BPA-2; BPAG2; COL17A1; ERED; LAD-1
UniProt ID: (Human) Q9UMD9
Entrez Gene ID: (Human) 1308
