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Application
产品信息
MA5-31984
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SR46-05
抗原
Recombinant protein within Human Collagen XVII aa 1313-1420
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2809278
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 180 kDa bullous pemphigoid antigen 2; alpha 1 type XVII collagen; bA16H23.2 (collagen, type XVII, alpha 1 (BP180)); Bullous pemphigoid antigen 2; bullous pemphigoid antigen 2 (180kD); Collagen alpha-1(XVII) chain; collagen XVII, alpha-1 polypeptide; collagen, type XVII, alpha 1; procollagen, type XVII, alpha 1; type XVII collagen alpha-1
基因别名: BA16H23.2; BP180; BPA-2; Bpag; BPAG2; COL17A1; ERED; LAD-1
UniProt ID: (Human) Q9UMD9, (Mouse) Q07563
Entrez Gene ID: (Human) 1308, (Rat) 294027, (Mouse) 12821
