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Antibody detects endogenous levels of total Collagen IV alpha 2.
Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha-2 collagen type IV; canstatin; Collagen alpha-2(IV) chain; procollagen, type IV, alpha 2
基因别名: Col4a-2; COL4A2; ICH; POREN2
UniProt ID: (Human) P08572, (Mouse) P08122
Entrez Gene ID: (Human) 1284, (Rat) 306628, (Mouse) 12827