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产品信息
PA5-61138
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640068
产品详细信息
Immunogen sequence: ARTGHTALRR VVSGCRPKSA TAAGAQAPVR NGRYLASCGI LMSRTLPLHT SILPKEICAR TFFKITAPLI NKRK
Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 64%.
靶标信息
COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.
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生物信息学
蛋白别名: Coenzyme Q-binding protein COQ10 homolog B, mitochondrial; coenzyme Q10 homolog B
基因别名: COQ10B
UniProt ID: (Human) Q9H8M1
Entrez Gene ID: (Human) 80219
