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Immunogen sequence: ALRNLSTGA AHSEGFSVQE QLATGGILWF PDLTAPDSTW ILPISVGVIN LLIVEICALQ KIGMSRFQTY ITYFVRAMSV LMIPIAATVP SSIVLYWLCS SFVGLSQNLL LRSPGFRQLC RIPSTKSDSE TPYKDIFAAF NTKFISRK (187-333 aa encoded by BC101684)
COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COX18 cytochrome c oxidase assembly factor; COX18 cytochrome c oxidase assembly homolog; COX18Hs; cytochrome c oxidase assembly homolog 18; Cytochrome c oxidase assembly protein 18; Cytochrome c oxidase assembly protein COX18, mitochondrial; mitochondrial inner membrane protein COX18
基因别名: BC038311; COX18; COX18HS; OXA1L2
UniProt ID: (Human) Q8N8Q8, (Mouse) Q8VC74
Entrez Gene ID: (Human) 285521, (Mouse) 231430