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产品信息
PA5-61990
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640093
产品详细信息
Immunogen sequence: AYQHYILAKV ENLQPEIKTI ARHLNQEVAV RANQLGWSKR DARLTYLKNM RRLISELYVR DNC
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.
靶标信息
COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COX18 cytochrome c oxidase assembly factor; COX18Hs; cytochrome c oxidase assembly homolog 18; Cytochrome c oxidase assembly protein 18; Cytochrome c oxidase assembly protein COX18, mitochondrial
基因别名: COX18; COX18HS; OXA1L2
UniProt ID: (Human) Q8N8Q8
Entrez Gene ID: (Human) 285521
