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Antibody detects endogenous levels of total Cytochrome c Oxidase 3.
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
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蛋白别名: Co3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3
基因别名: COIII; COXIII; MT-CO3; MTCO3
UniProt ID: (Mouse) P00416
Entrez Gene ID: (Mouse) 17710
分子生物学功能:
oxidase