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Antibody detects endogenous levels of total COX6C.
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytochrome c oxidase polypeptide VIc; Cytochrome c oxidase polypeptide VIc-2; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase subunit 6C-2; cytochrome c oxidase subunit VIc preprotein; cytochrome oxidase subunit VIc; EC 1.9.3.1
基因别名: COVIc; COX-VIc; COX6C; Cox6c2
UniProt ID: (Human) P09669, (Mouse) Q9CPQ1, (Rat) P11951
Entrez Gene ID: (Human) 1345, (Mouse) 12864, (Rat) 54322
分子生物学功能:
oxidase