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产品信息
CL48812780100UL
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
靶标信息
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centriolar coiled coil protein 110kDa; centriolar coiled-coil protein 110kDa; Centriolar coiled-coil protein of 110 kDa; centrosomal protein CP110; Centrosomal protein of 110 kDa; CEP1; CNTRL; CP110; FAN
基因别名: CCP110; CEP110; CP110; KIAA0419
UniProt ID: (Human) O43303
Entrez Gene ID: (Human) 9738
