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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha' beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: casein kinase 1, gamma 1; Casein kinase I isoform gamma-1; CK I gamma1; CK-I gamma1; CK1G1; CKI gamma 1; CKI gamma-1; CKI gamma1; CKI- gamma1; CKI-gamma 1; CKI-gamma-1; KC1G1
基因别名: CK1gamma1; CSNK1G1
UniProt ID: (Human) Q9HCP0
Entrez Gene ID: (Human) 53944