Proteintech

CTBP1 Monoclonal Antibody (1C4B2), CoraLite® 594

查看其他23个CtBP1抗体

抗体检测数据 (2)

CTBP1 Antibody in Immunocytochemistry (ICC/IF)

CTBP1 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 2

CTBP1 Antibody (CL594-66995) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CL594-66995 (CTBP1 antibody) at dilution of 1:100

CTBP1 Antibody in Immunocytochemistry (ICC/IF)

CTBP1 Antibody in Flow Cytometry (Flow)

Product Image Gallery

CTBP1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CL594-66995 (CTBP1 antibody) at dilution of 1:100

CTBP1 Antibody in Flow Cytometry (Flow) — 1X10^6 HepG2 cells were intracellularly stained with 0.2 µg CoraLite®594 Anti-Human CTBP1 (Product # CL594-66995, Clone:1C4B2) (red), or 0.2 µg Mouse IgG1 Isotype Control (CL594-66360, Clone: T1F8D3F10) (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011).

产品信息

CL594-66995

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

1:50-1:500

-

流式细胞分析 (Flow)

Assay-dependent

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

1C4B2

抗原

Full length CtBP1 protein.

偶联物

CoraLite® 594 CoraLite® 594 CoraLite® 594

激发/发射光谱

593/614 nm

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.3, with 0.5% BSA, 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20° C, store in dark

运输条件

Wet ice

靶标信息

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: 50 kDa BFA-dependent ADP-ribosylation substrate; 50-kDa BFA-induced ADP-ribosylated substrate; BARS-50; brefeldin A-ADP-riboslyated substrate; brefeldin A-ribosylated substrate; C-terminal-binding protein 1; C-terminal-binding protein 3; C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate; CtBP1; CtBP3; MGC104684

查看更多收起

基因别名: 50-kDaBFA-inducedADP-ribosylatedsubstrate; BARS; BARS-50; CTBP; CTBP1; CtBP1-L; CtBP1-S; Ctbp3; CtBP3/BARS; D4S115h; D5H4S115; D5H4S115E

查看更多收起

UniProt ID: (Human) Q13363, (Rat) Q9Z2F5, (Mouse) O88712

查看更多收起

Entrez Gene ID: (Human) 1487, (Rat) 29382, (Mouse) 13016

查看更多收起

RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor protein domain specific binding protein homodimerization activity NAD binding repressing transcription factor binding transcription corepressor activity transferase activity, transferring acyl groups C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity aldo-keto reductase (NADP) activity isocitrate dehydrogenase activity mevaldate reductase activity gluconate dehydrogenase activity steroid dehydrogenase activity oxidoreductase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-CH group of donors (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity 3-ketoglucose-reductase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity transcription cofactor

参与通路

negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated protein phosphorylation negative regulation of cell proliferation viral genome replication positive regulation of histone deacetylation negative regulation of histone acetylation negative regulation of transcription, DNA-templated white fat cell differentiation regulation of cell cycle oxidation-reduction process negative regulation of histone H4 acetylation negative regulation of transcription from RNA polymerase II promoter by histone modification membrane fusion regulation of transcription, DNA-templated transcription from RNA polymerase II promoter metabolic process cell differentiation