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产品信息
H00001487-M01
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2G7
抗原
CTBP1 (AAH53320, 1 a.a. approximately 429 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MSGVRPPIMN GPLHPRPLVA LLDGRDCTVE MPILKDVATV AFCDAQSTQE IHEKVLNEAV GALMYHTITL TREDLEKFKA LRIIVRIGSG FDNIDIKSAG DLGIAVCNVP AASVEETADS TLCHILNLYR RATWLHQALR EGTRVQSVEQ IREVASGAAR IRGETLGIIG LGRVGQAVAL RAKAFGFNVL FYDPYLSDGV ERALGLQRVS TLQDLLFHSD CVTLHCGLNE HNHHLINDFT VKQMRQGAFL VNTARGGLVD EKALAQALKE GRIRGAALDV HESEPFSFSQ GPLKDAPNLI CTPHAAWYSE QASIEMREEA AREIRRAITG RIPDSLKNCV NKDHLTAATH WASMDPAVVH PELNGAAYRY PPGVVGVAPT GIPAAVEGIV PSAMSLSHGL PPVAHPPHAP SPGQTVKPEA DRDHASDQL
靶标信息
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brefeldin A-ribosylated substrate; C-terminal-binding protein 1; CtBP1; MGC104684
基因别名: BARS; CTBP; CTBP1
UniProt ID: (Human) Q13363
Entrez Gene ID: (Human) 1487
RNA polymerase II transcription corepressor activity
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
transcription factor binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
protein domain specific binding
protein homodimerization activity
NAD binding
repressing transcription factor binding
transcription cofactor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
protein phosphorylation
negative regulation of cell proliferation
viral genome replication
positive regulation of histone deacetylation
negative regulation of histone acetylation
negative regulation of transcription, DNA-templated
white fat cell differentiation
regulation of cell cycle
oxidation-reduction process
negative regulation of histone H4 acetylation
negative regulation of transcription from RNA polymerase II promoter by histone modification
